V023-5195 Screening compound: ethyl 1-[3-amino-2-(2-chlorophenyl)-4-(4-fluorophenyl)-2H-pyrazolo[3,4-d]pyrimidin-6-yl]piperidine-3-carboxylate

V023-5195 Screening compound: ethyl 1-[3-amino-2-(2-chlorophenyl)-4-(4-fluorophenyl)-2H-pyrazolo[3,4-d]pyrimidin-6-yl]piperidine-3-carboxylate
V023-5195 Screening compound: ethyl 1-[3-amino-2-(2-chlorophenyl)-4-(4-fluorophenyl)-2H-pyrazolo[3,4-d]pyrimidin-6-yl]piperidine-3-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound V023-5195
ethyl 1-[3-amino-2-(2-chlorophenyl)-4-(4-fluorophenyl)-2H-pyrazolo[3,4-d]pyrimidin-6-yl]piperidine-3-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V023-5195

Molecular Formula

C25H24ClFN6O2 (C25 H24 ClFN6 O2)

Compound Name

ethyl 1-[3-amino-2-(2-chlorophenyl)-4-(4-fluorophenyl)-2H-pyrazolo[3,4-d]pyrimidin-6-yl]piperidine-3-carboxylate

IUPAC name

ethyl 1-[3-amino-2-(2-chlorophenyl)-4-(4-fluorophenyl)-2H-pyrazolo[34-d]pyrimidin-6-yl]piperidine-3-carboxylate

SMILES

CCOC(C(CCC1)CN1c(nc(c1c2N)-c(cc3)ccc3F)nc1nn2-c(cccc1)c1Cl)=O

InChI

InChI=1S/C25H24ClFN6O2/c1-2-35-24(34)16-6-5-13-32(14-16)25-29-21(15-9-11-17(27)12-10-15)20-22(28)33(31-23(20)30-25)19-8-4-3-7-18(19)26/h3-4,7-12,16H,2,5-6,13-14,28H2,1H3/t16-/m0/s1

InChI Key

JIWHHGBWQFDCPQ-INIZCTEOSA-N

MDL Number (MFCD)

MFCD14248514

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

494.96

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

5.072

Distribution Coefficient, logD

5.071

Water Solubility, LogSw

-5.44

Polar Surface Area

76.207

Acid Dissociation Constant (pKa)

19.75

Base Dissociation Constant (pKb)

4.15

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

28.00

V023-5195 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with V023-5195 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V023-5195?
Check Price and Availability of V023-5195, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V023-5195 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V023-5195
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V023-5195
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V023-5195 available by request