V024-0743 Screening compound: 2-(4-isobutyrylpiperazino)-6-{[4-(3-methylphenyl)piperazino]methyl}-4(3H)-pyrimidinone

V024-0743 Screening compound: 2-(4-isobutyrylpiperazino)-6-{[4-(3-methylphenyl)piperazino]methyl}-4(3H)-pyrimidinone
V024-0743 Screening compound: 2-(4-isobutyrylpiperazino)-6-{[4-(3-methylphenyl)piperazino]methyl}-4(3H)-pyrimidinone alternative view

Chemical Structure Depiction of ChemDiv screening compound V024-0743
2-(4-isobutyrylpiperazino)-6-{[4-(3-methylphenyl)piperazino]methyl}-4(3H)-pyrimidinone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V024-0743

Molecular Formula

C24H34N6O2 (C24 H34 N6 O2)

Compound Name

2-(4-isobutyrylpiperazino)-6-{[4-(3-methylphenyl)piperazino]methyl}-4(3H)-pyrimidinone

IUPAC name

6-{[4-(3-methylphenyl)piperazin-1-yl]methyl}-2-[4-(2-methylpropanoyl)piperazin-1-yl]-34-dihydropyrimidin-4-one

SMILES

CC(C)C(N(CC1)CCN1C(N1)=NC(CN(CC2)CCN2c2cc(C)ccc2)=CC1=O)=O

InChI

InChI=1S/C24H34N6O2/c1-18(2)23(32)29-11-13-30(14-12-29)24-25-20(16-22(31)26-24)17-27-7-9-28(10-8-27)21-6-4-5-19(3)15-21/h4-6,15-16,18H,7-14,17H2,1-3H3,(H,25,26,31)

InChI Key

PTIIJKWUDBEGPN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19859947

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

438.57

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.038

Distribution Coefficient, logD

0.536

Water Solubility, LogSw

-2.74

Polar Surface Area

62.083

Acid Dissociation Constant (pKa)

8.87

Base Dissociation Constant (pKb)

7.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

54.17

V024-0743 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with V024-0743 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V024-0743?
Check Price and Availability of V024-0743, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V024-0743 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V024-0743
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V024-0743
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V024-0743 available by request