V024-1744 Screening compound: 3-({3'-cyclobutanecarbonyl-5-fluoro-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-1-yl}methyl)benzonitrile

V024-1744 Screening compound: 3-({3'-cyclobutanecarbonyl-5-fluoro-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-1-yl}methyl)benzonitrile
V024-1744 Screening compound: 3-({3'-cyclobutanecarbonyl-5-fluoro-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-1-yl}methyl)benzonitrile alternative view

Chemical Structure Depiction of ChemDiv screening compound V024-1744
3-({3'-cyclobutanecarbonyl-5-fluoro-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-1-yl}methyl)benzonitrile

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V024-1744

Molecular Formula

C23H20FN3O2S (C23 H20 FN3 O2 S)

Compound Name

3-({3'-cyclobutanecarbonyl-5-fluoro-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-1-yl}methyl)benzonitrile

IUPAC name

3-({3'-cyclobutanecarbonyl-5-fluoro-2-oxo-12-dihydrospiro[indole-32'-[13]thiazolidin]-1-yl}methyl)benzonitrile

SMILES

N#Cc1cccc(CN(C(C23SCCN2C(C2CCC2)=O)=O)c(cc2)c3cc2F)c1

InChI

InChI=1S/C23H20FN3O2S/c24-18-7-8-20-19(12-18)23(27(9-10-30-23)21(28)17-5-2-6-17)22(29)26(20)14-16-4-1-3-15(11-16)13-25/h1,3-4,7-8,11-12,17H,2,5-6,9-10,14H2/t23-/m0/s1

InChI Key

VZNCYQIGPUFMFI-QHCPKHFHSA-N

MDL Number (MFCD)

MFCD19872381

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.5

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.436

Distribution Coefficient, logD

3.436

Water Solubility, LogSw

-3.76

Polar Surface Area

49.159

Acid Dissociation Constant (pKa)

23.04

Base Dissociation Constant (pKb)

-5.60

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

34.80

V024-1744 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

RAR (Nuclear receptors) Ligands Library (6524 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • PPI modulators
Therapeutical areas:
  • Cancer
  • Respiratory tract
  • Eye
  • Male
  • Female
  • Hemic and lymphatic
  • Congenital
  • Skin
  • Endocrine
  • Immune system
Targets:
  • Nuclear receptors
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with V024-1744 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V024-1744?
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What is the minimum amount of V024-1744 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V024-1744
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V024-1744
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V024-1744 available by request