V024-1860 Screening compound: 5-({[2-cyclopentanecarbonyl-1-(3-methylphenyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]oxy}methyl)-N-[2-(pyridin-2-yl)ethyl]furan-2-carboxamide

V024-1860 Screening compound: 5-({[2-cyclopentanecarbonyl-1-(3-methylphenyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]oxy}methyl)-N-[2-(pyridin-2-yl)ethyl]furan-2-carboxamide
V024-1860 Screening compound: 5-({[2-cyclopentanecarbonyl-1-(3-methylphenyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]oxy}methyl)-N-[2-(pyridin-2-yl)ethyl]furan-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V024-1860
5-({[2-cyclopentanecarbonyl-1-(3-methylphenyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]oxy}methyl)-N-[2-(pyridin-2-yl)ethyl]furan-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V024-1860

Molecular Formula

C35H37N3O4 (C35 H37 N3 O4)

Compound Name

5-({[2-cyclopentanecarbonyl-1-(3-methylphenyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]oxy}methyl)-N-[2-(pyridin-2-yl)ethyl]furan-2-carboxamide

IUPAC name

5-({[2-cyclopentanecarbonyl-1-(3-methylphenyl)-1234-tetrahydroisoquinolin-7-yl]oxy}methyl)-N-[2-(pyridin-2-yl)ethyl]furan-2-carboxamide

SMILES

Cc1cccc(C(c2c(CC3)ccc(OCc4ccc(C(NCCc5ncccc5)=O)o4)c2)N3C(C2CCCC2)=O)c1

InChI

InChI=1S/C35H37N3O4/c1-24-7-6-10-27(21-24)33-31-22-29(13-12-25(31)17-20-38(33)35(40)26-8-2-3-9-26)41-23-30-14-15-32(42-30)34(39)37-19-16-28-11-4-5-18-36-28/h4-7,10-15,18,21-22,26,33H,2-3,8-9,16-17,19-20,23H2,1H3,(H,37,39)/t33-/m0/s1

InChI Key

GDJZIDOZKRLVEM-XIFFEERXSA-N

MDL Number (MFCD)

MFCD19917796

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

563.7

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

6.239

Distribution Coefficient, logD

6.238

Water Solubility, LogSw

-5.35

Polar Surface Area

65.286

Acid Dissociation Constant (pKa)

13.84

Base Dissociation Constant (pKb)

4.06

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

34.30

V024-1860 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Lipid Metabolism Library (9174 compounds)

MCL1 Targeted Library (12200 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cardiovascular
  • Metabolic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • GPCR
  • Phosphatases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with V024-1860 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V024-1860?
Check Price and Availability of V024-1860, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V024-1860 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V024-1860
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V024-1860
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V024-1860 available by request