V024-6458 Screening compound: 2-({[2,6-bis(propan-2-yl)phenyl]carbamoyl}(3-methoxypropyl)amino)-N-[3-tert-butyl-1-(2,4-dimethylphenyl)-1H-pyrazol-5-yl]acetamide

V024-6458 Screening compound: 2-({[2,6-bis(propan-2-yl)phenyl]carbamoyl}(3-methoxypropyl)amino)-N-[3-tert-butyl-1-(2,4-dimethylphenyl)-1H-pyrazol-5-yl]acetamide
V024-6458 Screening compound: 2-({[2,6-bis(propan-2-yl)phenyl]carbamoyl}(3-methoxypropyl)amino)-N-[3-tert-butyl-1-(2,4-dimethylphenyl)-1H-pyrazol-5-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V024-6458
2-({[2,6-bis(propan-2-yl)phenyl]carbamoyl}(3-methoxypropyl)amino)-N-[3-tert-butyl-1-(2,4-dimethylphenyl)-1H-pyrazol-5-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V024-6458

Molecular Formula

C34H49N5O3 (C34 H49 N5 O3)

Compound Name

2-({[2,6-bis(propan-2-yl)phenyl]carbamoyl}(3-methoxypropyl)amino)-N-[3-tert-butyl-1-(2,4-dimethylphenyl)-1H-pyrazol-5-yl]acetamide

IUPAC name

2-({[26-bis(propan-2-yl)phenyl]carbamoyl}(3-methoxypropyl)amino)-N-[3-tert-butyl-1-(24-dimethylphenyl)-1H-pyrazol-5-yl]acetamide

SMILES

CC(C)c1cccc(C(C)C)c1NC(N(CCCOC)CC(Nc1cc(C(C)(C)C)nn1-c1c(C)cc(C)cc1)=O)=O

InChI

InChI=1S/C34H49N5O3/c1-22(2)26-13-11-14-27(23(3)4)32(26)36-33(41)38(17-12-18-42-10)21-31(40)35-30-20-29(34(7,8)9)37-39(30)28-16-15-24(5)19-25(28)6/h11,13-16,19-20,22-23H,12,17-18,21H2,1-10H3,(H,35,40)(H,36,41)

InChI Key

QBKGXBMQLGBMEU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19714593

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

575.79

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

15.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

6.899

Distribution Coefficient, logD

6.898

Water Solubility, LogSw

-5.54

Polar Surface Area

69.479

Acid Dissociation Constant (pKa)

10.61

Base Dissociation Constant (pKb)

4.57

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

V024-6458 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with V024-6458 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V024-6458?
Check Price and Availability of V024-6458, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V024-6458 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V024-6458
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V024-6458
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V024-6458 available by request