V024-8221 Screening compound: 4-[({4-[4-(2-chlorophenyl)piperazino]-6-phenyl-2-pyrimidinyl}sulfanyl)methyl]-N~1~-(tetrahydro-2-furanylmethyl)benzamide

V024-8221 Screening compound: 4-[({4-[4-(2-chlorophenyl)piperazino]-6-phenyl-2-pyrimidinyl}sulfanyl)methyl]-N~1~-(tetrahydro-2-furanylmethyl)benzamide
V024-8221 Screening compound: 4-[({4-[4-(2-chlorophenyl)piperazino]-6-phenyl-2-pyrimidinyl}sulfanyl)methyl]-N~1~-(tetrahydro-2-furanylmethyl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V024-8221
4-[({4-[4-(2-chlorophenyl)piperazino]-6-phenyl-2-pyrimidinyl}sulfanyl)methyl]-N~1~-(tetrahydro-2-furanylmethyl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V024-8221

Molecular Formula

C33H34ClN5O2S (C33 H34 ClN5 O2 S)

Compound Name

4-[({4-[4-(2-chlorophenyl)piperazino]-6-phenyl-2-pyrimidinyl}sulfanyl)methyl]-N~1~-(tetrahydro-2-furanylmethyl)benzamide

IUPAC name

4-[({4-[4-(2-chlorophenyl)piperazin-1-yl]-6-phenylpyrimidin-2-yl}sulfanyl)methyl]-N-[(oxolan-2-yl)methyl]benzamide

SMILES

O=C(c1ccc(CSc2nc(-c3ccccc3)cc(N(CC3)CCN3c(cccc3)c3Cl)n2)cc1)NCC1OCCC1

InChI

InChI=1S/C33H34ClN5O2S/c34-28-10-4-5-11-30(28)38-16-18-39(19-17-38)31-21-29(25-7-2-1-3-8-25)36-33(37-31)42-23-24-12-14-26(15-13-24)32(40)35-22-27-9-6-20-41-27/h1-5,7-8,10-15,21,27H,6,9,16-20,22-23H2,(H,35,40)/t27-/m1/s1

InChI Key

WNWCOSVXRDVGSF-HHHXNRCGSA-N

MDL Number (MFCD)

MFCD19816478

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

600.18

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

6.640

Distribution Coefficient, logD

6.640

Water Solubility, LogSw

-6.35

Polar Surface Area

55.932

Acid Dissociation Constant (pKa)

12.79

Base Dissociation Constant (pKb)

4.20

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

30.30

V024-8221 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with V024-8221 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V024-8221?
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What is the minimum amount of V024-8221 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V024-8221
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V024-8221
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V024-8221 available by request