V024-8520 Screening compound: N-(1,3-diphenyl-1H-pyrazol-5-yl)-2-{N-[(furan-2-yl)methyl]-2-(4-methoxyphenyl)acetamido}acetamide

V024-8520 Screening compound: N-(1,3-diphenyl-1H-pyrazol-5-yl)-2-{N-[(furan-2-yl)methyl]-2-(4-methoxyphenyl)acetamido}acetamide
V024-8520 Screening compound: N-(1,3-diphenyl-1H-pyrazol-5-yl)-2-{N-[(furan-2-yl)methyl]-2-(4-methoxyphenyl)acetamido}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V024-8520
N-(1,3-diphenyl-1H-pyrazol-5-yl)-2-{N-[(furan-2-yl)methyl]-2-(4-methoxyphenyl)acetamido}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V024-8520

Molecular Formula

C31H28N4O4 (C31 H28 N4 O4)

Compound Name

N-(1,3-diphenyl-1H-pyrazol-5-yl)-2-{N-[(furan-2-yl)methyl]-2-(4-methoxyphenyl)acetamido}acetamide

IUPAC name

N-(13-diphenyl-1H-pyrazol-5-yl)-2-{N-[(furan-2-yl)methyl]-2-(4-methoxyphenyl)acetamido}acetamide

SMILES

COc1ccc(CC(N(CC(Nc2cc(-c3ccccc3)nn2-c2ccccc2)=O)Cc2ccco2)=O)cc1

InChI

InChI=1S/C31H28N4O4/c1-38-26-16-14-23(15-17-26)19-31(37)34(21-27-13-8-18-39-27)22-30(36)32-29-20-28(24-9-4-2-5-10-24)33-35(29)25-11-6-3-7-12-25/h2-18,20H,19,21-22H2,1H3,(H,32,36)

InChI Key

JGUOFGSVAFLUML-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19717080

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

520.59

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

12.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

5.554

Distribution Coefficient, logD

5.554

Water Solubility, LogSw

-5.45

Polar Surface Area

68.256

Acid Dissociation Constant (pKa)

13.33

Base Dissociation Constant (pKb)

-2.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.90

V024-8520 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

SH2 Library (10483 compounds)

PD-1/L1 Library (498 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Endocrine
  • Cancer
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Mechanism of action:
  • PPI modulators
Targets:
  • Others

References: we are preparing a list of scientific research reports with V024-8520 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V024-8520?
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What is the minimum amount of V024-8520 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V024-8520
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V024-8520
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V024-8520 available by request