V024-9977 Screening compound: N-(4-{[1-(2-chlorophenyl)-6-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino}cyclohexyl)-4-fluorobenzamide

V024-9977 Screening compound: N-(4-{[1-(2-chlorophenyl)-6-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino}cyclohexyl)-4-fluorobenzamide
V024-9977 Screening compound: N-(4-{[1-(2-chlorophenyl)-6-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino}cyclohexyl)-4-fluorobenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V024-9977
N-(4-{[1-(2-chlorophenyl)-6-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino}cyclohexyl)-4-fluorobenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V024-9977

Molecular Formula

C27H28ClFN6O (C27 H28 ClFN6 O)

Compound Name

N-(4-{[1-(2-chlorophenyl)-6-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino}cyclohexyl)-4-fluorobenzamide

IUPAC name

N-(4-{[1-(2-chlorophenyl)-6-(propan-2-yl)-1H-pyrazolo[34-d]pyrimidin-4-yl]amino}cyclohexyl)-4-fluorobenzamide

SMILES

CC(C)c1nc(NC(CC2)CCC2NC(c(cc2)ccc2F)=O)c(cnn2-c(cccc3)c3Cl)c2n1

InChI

InChI=1S/C27H28ClFN6O/c1-16(2)24-33-25(21-15-30-35(26(21)34-24)23-6-4-3-5-22(23)28)31-19-11-13-20(14-12-19)32-27(36)17-7-9-18(29)10-8-17/h3-10,15-16,19-20H,11-14H2,1-2H3,(H,32,36)(H,31,33,34)

InChI Key

PEQXUKWWYJJAMC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14259712

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

507.01

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.825

Distribution Coefficient, logD

5.811

Water Solubility, LogSw

-6.02

Polar Surface Area

67.482

Acid Dissociation Constant (pKa)

13.23

Base Dissociation Constant (pKb)

5.93

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

V024-9977 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

CNS Targets (44014 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with V024-9977 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V024-9977?
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What is the minimum amount of V024-9977 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V024-9977
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V024-9977
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V024-9977 available by request