V025-8786 Screening compound: N-(4-chlorophenyl)-1-[(3,4-difluorophenyl)methyl]-5-methyl-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide

V025-8786 Screening compound: N-(4-chlorophenyl)-1-[(3,4-difluorophenyl)methyl]-5-methyl-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide
V025-8786 Screening compound: N-(4-chlorophenyl)-1-[(3,4-difluorophenyl)methyl]-5-methyl-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V025-8786
N-(4-chlorophenyl)-1-[(3,4-difluorophenyl)methyl]-5-methyl-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V025-8786

Molecular Formula

C25H20ClF2N3O2S (C25 H20 ClF2 N3 O2 S)

Compound Name

N-(4-chlorophenyl)-1-[(3,4-difluorophenyl)methyl]-5-methyl-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide

IUPAC name

N-(4-chlorophenyl)-1-[(34-difluorophenyl)methyl]-5-methyl-2-oxo-12-dihydrospiro[indole-32'-[13]thiazolidine]-3'-carboxamide

SMILES

Cc(cc1)cc(C23SCCN2C(Nc(cc2)ccc2Cl)=O)c1N(Cc(cc1)cc(F)c1F)C3=O

InChI

InChI=1S/C25H20ClF2N3O2S/c1-15-2-9-22-19(12-15)25(23(32)30(22)14-16-3-8-20(27)21(28)13-16)31(10-11-34-25)24(33)29-18-6-4-17(26)5-7-18/h2-9,12-13H,10-11,14H2,1H3,(H,29,33)/t25-/m0/s1

InChI Key

CODQPOVHHMYLPA-VWLOTQADSA-N

MDL Number (MFCD)

MFCD19871723

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

499.97

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.089

Distribution Coefficient, logD

6.089

Water Solubility, LogSw

-5.97

Polar Surface Area

40.400

Acid Dissociation Constant (pKa)

12.71

Base Dissociation Constant (pKb)

-1.70

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

20.00

V025-8786 in Drug Discovery

Included in Screening Libraries

Anti-infective Library (19449 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with V025-8786 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V025-8786?
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What is the minimum amount of V025-8786 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V025-8786
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V025-8786
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V025-8786 available by request