V025-8843 Screening compound: 2-(butan-2-yl)-5-[(2,4-dichlorophenyl)methyl]-4-methyl-6-[4-(oxolane-3-carbonyl)piperazin-1-yl]pyrimidine

V025-8843 Screening compound: 2-(butan-2-yl)-5-[(2,4-dichlorophenyl)methyl]-4-methyl-6-[4-(oxolane-3-carbonyl)piperazin-1-yl]pyrimidine
V025-8843 Screening compound: 2-(butan-2-yl)-5-[(2,4-dichlorophenyl)methyl]-4-methyl-6-[4-(oxolane-3-carbonyl)piperazin-1-yl]pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound V025-8843
2-(butan-2-yl)-5-[(2,4-dichlorophenyl)methyl]-4-methyl-6-[4-(oxolane-3-carbonyl)piperazin-1-yl]pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V025-8843

Molecular Formula

C25H32Cl2N4O2 (C25 H32 Cl2 N4 O2)

Compound Name

2-(butan-2-yl)-5-[(2,4-dichlorophenyl)methyl]-4-methyl-6-[4-(oxolane-3-carbonyl)piperazin-1-yl]pyrimidine

IUPAC name

2-(butan-2-yl)-5-[(24-dichlorophenyl)methyl]-4-methyl-6-[4-(oxolane-3-carbonyl)piperazin-1-yl]pyrimidine

SMILES

CCC(C)c1nc(N(CC2)CCN2C(C2COCC2)=O)c(Cc(ccc(Cl)c2)c2Cl)c(C)n1

InChI

InChI=1S/C25H32Cl2N4O2/c1-4-16(2)23-28-17(3)21(13-18-5-6-20(26)14-22(18)27)24(29-23)30-8-10-31(11-9-30)25(32)19-7-12-33-15-19/h5-6,14,16,19H,4,7-13,15H2,1-3H3

InChI Key

OQIUTEPTAUIOHZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19789767

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

491.46

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.844

Distribution Coefficient, logD

5.677

Water Solubility, LogSw

-5.95

Polar Surface Area

47.921

Acid Dissociation Constant (pKa)

20.37

Base Dissociation Constant (pKb)

7.07

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

56.00

V025-8843 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with V025-8843 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V025-8843?
Check Price and Availability of V025-8843, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V025-8843 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V025-8843
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V025-8843
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V025-8843 available by request