V027-2486 Screening compound: N~2~-cyclopropyl-5-{[(4-ethyl-6-{4-[(E)-3-phenyl-2-propenyl]piperazino}-2-pyrimidinyl)sulfanyl]methyl}-2-furamide

V027-2486 Screening compound: N~2~-cyclopropyl-5-{[(4-ethyl-6-{4-[(E)-3-phenyl-2-propenyl]piperazino}-2-pyrimidinyl)sulfanyl]methyl}-2-furamide
V027-2486 Screening compound: N~2~-cyclopropyl-5-{[(4-ethyl-6-{4-[(E)-3-phenyl-2-propenyl]piperazino}-2-pyrimidinyl)sulfanyl]methyl}-2-furamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V027-2486
N~2~-cyclopropyl-5-{[(4-ethyl-6-{4-[(E)-3-phenyl-2-propenyl]piperazino}-2-pyrimidinyl)sulfanyl]methyl}-2-furamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V027-2486

Molecular Formula

C28H33N5O2S (C28 H33 N5 O2 S)

Compound Name

N~2~-cyclopropyl-5-{[(4-ethyl-6-{4-[(E)-3-phenyl-2-propenyl]piperazino}-2-pyrimidinyl)sulfanyl]methyl}-2-furamide

IUPAC name

n/a

SMILES

CCc1nc(SCc2ccc(C(NC3CC3)=O)o2)nc(N2CCN(C/C=C/c3ccccc3)CC2)c1

InChI

InChI=1S/C28H33N5O2S/c1-2-22-19-26(33-17-15-32(16-18-33)14-6-9-21-7-4-3-5-8-21)31-28(30-22)36-20-24-12-13-25(35-24)27(34)29-23-10-11-23/h3-9,12-13,19,23H,2,10-11,14-18,20H2,1H3,(H,29,34)

InChI Key

ZTQPAZXYQIPUQE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19815333

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

503.67

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.813

Distribution Coefficient, logD

5.799

Water Solubility, LogSw

-5.41

Polar Surface Area

56.501

Acid Dissociation Constant (pKa)

12.97

Base Dissociation Constant (pKb)

5.89

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.30

V027-2486 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with V027-2486 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V027-2486?
Check Price and Availability of V027-2486, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V027-2486 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V027-2486
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V027-2486
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V027-2486 available by request