V027-4360 Screening compound: methyl 6-(3-{[(4-cyanophenyl)carbamoyl]amino}phenyl)-8-methyl-2H,3H,4H,6H-pyrimido[2,1-b][1,3]thiazine-7-carboxylate

V027-4360 Screening compound: methyl 6-(3-{[(4-cyanophenyl)carbamoyl]amino}phenyl)-8-methyl-2H,3H,4H,6H-pyrimido[2,1-b][1,3]thiazine-7-carboxylate
V027-4360 Screening compound: methyl 6-(3-{[(4-cyanophenyl)carbamoyl]amino}phenyl)-8-methyl-2H,3H,4H,6H-pyrimido[2,1-b][1,3]thiazine-7-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound V027-4360
methyl 6-(3-{[(4-cyanophenyl)carbamoyl]amino}phenyl)-8-methyl-2H,3H,4H,6H-pyrimido[2,1-b][1,3]thiazine-7-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V027-4360

Molecular Formula

C24H23N5O3S (C24 H23 N5 O3 S)

Compound Name

methyl 6-(3-{[(4-cyanophenyl)carbamoyl]amino}phenyl)-8-methyl-2H,3H,4H,6H-pyrimido[2,1-b][1,3]thiazine-7-carboxylate

IUPAC name

methyl 6-(3-{[(4-cyanophenyl)carbamoyl]amino}phenyl)-8-methyl-2H3H4H6H-pyrimido[21-b][13]thiazine-7-carboxylate

SMILES

CC(N=C1SCCCN1C1c2cc(NC(Nc(cc3)ccc3C#N)=O)ccc2)=C1C(OC)=O

InChI

InChI=1S/C24H23N5O3S/c1-15-20(22(30)32-2)21(29-11-4-12-33-24(29)26-15)17-5-3-6-19(13-17)28-23(31)27-18-9-7-16(14-25)8-10-18/h3,5-10,13,21H,4,11-12H2,1-2H3,(H2,27,28,31)/t21-/m1/s1

InChI Key

ASFYRHLVNPCBPB-OAQYLSRUSA-N

MDL Number (MFCD)

MFCD19727468

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

461.54

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.266

Distribution Coefficient, logD

3.954

Water Solubility, LogSw

-4.22

Polar Surface Area

82.702

Acid Dissociation Constant (pKa)

12.11

Base Dissociation Constant (pKb)

7.42

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

25.00

V027-4360 in Drug Discovery

Included in Screening Libraries

Integrin Receptors Targeted library (1715 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Immune system
Targets:
  • Others

References: we are preparing a list of scientific research reports with V027-4360 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V027-4360?
Check Price and Availability of V027-4360, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V027-4360 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V027-4360
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V027-4360
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V027-4360 available by request