V027-4621 Screening compound: N-[3,5-bis(trifluoromethyl)phenyl]-3-(1H-indol-3-yl)-3-[4-(trifluoromethyl)phenyl]propanamide

V027-4621 Screening compound: N-[3,5-bis(trifluoromethyl)phenyl]-3-(1H-indol-3-yl)-3-[4-(trifluoromethyl)phenyl]propanamide
V027-4621 Screening compound: N-[3,5-bis(trifluoromethyl)phenyl]-3-(1H-indol-3-yl)-3-[4-(trifluoromethyl)phenyl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V027-4621
N-[3,5-bis(trifluoromethyl)phenyl]-3-(1H-indol-3-yl)-3-[4-(trifluoromethyl)phenyl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V027-4621

Molecular Formula

C26H17F9N2O (C26 H17 F9 N2 O)

Compound Name

N-[3,5-bis(trifluoromethyl)phenyl]-3-(1H-indol-3-yl)-3-[4-(trifluoromethyl)phenyl]propanamide

IUPAC name

N-[35-bis(trifluoromethyl)phenyl]-3-(1H-indol-3-yl)-3-[4-(trifluoromethyl)phenyl]propanamide

SMILES

O=C(CC(c1c[nH]c2c1cccc2)c1ccc(C(F)(F)F)cc1)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1

InChI

InChI=1S/C26H17F9N2O/c27-24(28,29)15-7-5-14(6-8-15)20(21-13-36-22-4-2-1-3-19(21)22)12-23(38)37-18-10-16(25(30,31)32)9-17(11-18)26(33,34)35/h1-11,13,20,36H,12H2,(H,37,38)/t20-/m1/s1

InChI Key

TVKOTGZKTLRWCK-HXUWFJFHSA-N

MDL Number (MFCD)

MFCD19776494

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

544.42

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

8.046

Distribution Coefficient, logD

7.265

Water Solubility, LogSw

-6.53

Polar Surface Area

32.715

Acid Dissociation Constant (pKa)

6.70

Base Dissociation Constant (pKb)

-1.40

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

19.20

V027-4621 in Drug Discovery

Included in Screening Libraries

Glucocorticoid receptors Library (4806 compounds)

Indole Derivatives (10091 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with V027-4621 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V027-4621?
Check Price and Availability of V027-4621, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V027-4621 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V027-4621
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V027-4621
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V027-4621 available by request