V027-4829 Screening compound: 2-(4-fluorophenyl)-6-(piperidin-1-yl)-4-[4-(propan-2-yl)phenyl]-2H-pyrazolo[3,4-d]pyrimidin-3-amine

V027-4829 Screening compound: 2-(4-fluorophenyl)-6-(piperidin-1-yl)-4-[4-(propan-2-yl)phenyl]-2H-pyrazolo[3,4-d]pyrimidin-3-amine
V027-4829 Screening compound: 2-(4-fluorophenyl)-6-(piperidin-1-yl)-4-[4-(propan-2-yl)phenyl]-2H-pyrazolo[3,4-d]pyrimidin-3-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound V027-4829
2-(4-fluorophenyl)-6-(piperidin-1-yl)-4-[4-(propan-2-yl)phenyl]-2H-pyrazolo[3,4-d]pyrimidin-3-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V027-4829

Molecular Formula

C25H27FN6 (C25 H27 FN6)

Compound Name

2-(4-fluorophenyl)-6-(piperidin-1-yl)-4-[4-(propan-2-yl)phenyl]-2H-pyrazolo[3,4-d]pyrimidin-3-amine

IUPAC name

2-(4-fluorophenyl)-6-(piperidin-1-yl)-4-[4-(propan-2-yl)phenyl]-2H-pyrazolo[34-d]pyrimidin-3-amine

SMILES

CC(C)c(cc1)ccc1-c(c1c2N)nc(N3CCCCC3)nc1nn2-c(cc1)ccc1F

InChI

InChI=1S/C25H27FN6/c1-16(2)17-6-8-18(9-7-17)22-21-23(27)32(20-12-10-19(26)11-13-20)30-24(21)29-25(28-22)31-14-4-3-5-15-31/h6-13,16H,3-5,14-15,27H2,1-2H3

InChI Key

NJGAEPYTGKZOSZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14249918

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

430.53

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

6.181

Distribution Coefficient, logD

6.180

Water Solubility, LogSw

-6.00

Polar Surface Area

55.821

Acid Dissociation Constant (pKa)

20.03

Base Dissociation Constant (pKb)

4.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.00

V027-4829 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with V027-4829 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V027-4829?
Check Price and Availability of V027-4829, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V027-4829 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V027-4829
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V027-4829
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V027-4829 available by request