V027-5737 Screening compound: 4-(3,4-difluorophenoxy)-6-{4-[(4-methylphenyl)methyl]piperazin-1-yl}pyrimidine

V027-5737 Screening compound: 4-(3,4-difluorophenoxy)-6-{4-[(4-methylphenyl)methyl]piperazin-1-yl}pyrimidine
V027-5737 Screening compound: 4-(3,4-difluorophenoxy)-6-{4-[(4-methylphenyl)methyl]piperazin-1-yl}pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound V027-5737
4-(3,4-difluorophenoxy)-6-{4-[(4-methylphenyl)methyl]piperazin-1-yl}pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V027-5737

Molecular Formula

C22H22F2N4O (C22 H22 F2 N4 O)

Compound Name

4-(3,4-difluorophenoxy)-6-{4-[(4-methylphenyl)methyl]piperazin-1-yl}pyrimidine

IUPAC name

4-(34-difluorophenoxy)-6-{4-[(4-methylphenyl)methyl]piperazin-1-yl}pyrimidine

SMILES

Cc1ccc(CN(CC2)CCN2c2cc(Oc(cc3)cc(F)c3F)ncn2)cc1

InChI

InChI=1S/C22H22F2N4O/c1-16-2-4-17(5-3-16)14-27-8-10-28(11-9-27)21-13-22(26-15-25-21)29-18-6-7-19(23)20(24)12-18/h2-7,12-13,15H,8-11,14H2,1H3

InChI Key

ZZTODGOEBCEKNI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19861337

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

396.44

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.559

Distribution Coefficient, logD

4.265

Water Solubility, LogSw

-4.38

Polar Surface Area

33.153

Acid Dissociation Constant (pKa)

22.82

Base Dissociation Constant (pKb)

7.39

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

V027-5737 in Drug Discovery

Included in Screening Libraries

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with V027-5737 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V027-5737?
Check Price and Availability of V027-5737, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V027-5737 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V027-5737
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V027-5737
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V027-5737 available by request