V027-6377 Screening compound: 2-chloro-N-(2-{[1-(3-chlorophenyl)-3,6-dimethyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino}ethyl)benzamide

V027-6377 Screening compound: 2-chloro-N-(2-{[1-(3-chlorophenyl)-3,6-dimethyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino}ethyl)benzamide
V027-6377 Screening compound: 2-chloro-N-(2-{[1-(3-chlorophenyl)-3,6-dimethyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino}ethyl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V027-6377
2-chloro-N-(2-{[1-(3-chlorophenyl)-3,6-dimethyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino}ethyl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V027-6377

Molecular Formula

C22H20Cl2N6O (C22 H20 Cl2 N6 O)

Compound Name

2-chloro-N-(2-{[1-(3-chlorophenyl)-3,6-dimethyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino}ethyl)benzamide

IUPAC name

2-chloro-N-(2-{[1-(3-chlorophenyl)-36-dimethyl-1H-pyrazolo[34-d]pyrimidin-4-yl]amino}ethyl)benzamide

SMILES

Cc(c1c2nc(C)nc1NCCNC(c(cccc1)c1Cl)=O)nn2-c1cc(Cl)ccc1

InChI

InChI=1S/C22H20Cl2N6O/c1-13-19-20(25-10-11-26-22(31)17-8-3-4-9-18(17)24)27-14(2)28-21(19)30(29-13)16-7-5-6-15(23)12-16/h3-9,12H,10-11H2,1-2H3,(H,26,31)(H,25,27,28)

InChI Key

CKZKWXYFZBEUTA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14256149

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

455.35

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.366

Distribution Coefficient, logD

4.244

Water Solubility, LogSw

-4.49

Polar Surface Area

68.445

Acid Dissociation Constant (pKa)

12.53

Base Dissociation Constant (pKb)

6.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

V027-6377 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic
Agro:
  • Agro

References: we are preparing a list of scientific research reports with V027-6377 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V027-6377?
Check Price and Availability of V027-6377, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V027-6377 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V027-6377
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V027-6377
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V027-6377 available by request