V027-7231 Screening compound: 1-{2-[(2,3-dichlorophenyl)amino]-1,3-thiazole-4-carbonyl}-N-{[3-(trifluoromethyl)phenyl]methyl}pyrrolidine-2-carboxamide

V027-7231 Screening compound: 1-{2-[(2,3-dichlorophenyl)amino]-1,3-thiazole-4-carbonyl}-N-{[3-(trifluoromethyl)phenyl]methyl}pyrrolidine-2-carboxamide
V027-7231 Screening compound: 1-{2-[(2,3-dichlorophenyl)amino]-1,3-thiazole-4-carbonyl}-N-{[3-(trifluoromethyl)phenyl]methyl}pyrrolidine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V027-7231
1-{2-[(2,3-dichlorophenyl)amino]-1,3-thiazole-4-carbonyl}-N-{[3-(trifluoromethyl)phenyl]methyl}pyrrolidine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V027-7231

Molecular Formula

C23H19Cl2F3N4O2S (C23 H19 Cl2 F3 N4 O2 S)

Compound Name

1-{2-[(2,3-dichlorophenyl)amino]-1,3-thiazole-4-carbonyl}-N-{[3-(trifluoromethyl)phenyl]methyl}pyrrolidine-2-carboxamide

IUPAC name

1-{2-[(23-dichlorophenyl)amino]-13-thiazole-4-carbonyl}-N-{[3-(trifluoromethyl)phenyl]methyl}pyrrolidine-2-carboxamide

SMILES

O=C(C(CCC1)N1C(c1csc(Nc2cccc(Cl)c2Cl)n1)=O)NCc1cc(C(F)(F)F)ccc1

InChI

InChI=1S/C23H19Cl2F3N4O2S/c24-15-6-2-7-16(19(15)25)30-22-31-17(12-35-22)21(34)32-9-3-8-18(32)20(33)29-11-13-4-1-5-14(10-13)23(26,27)28/h1-2,4-7,10,12,18H,3,8-9,11H2,(H,29,33)(H,30,31)/t18-/m0/s1

InChI Key

WRRDTYBUZJHVEJ-SFHVURJKSA-N

MDL Number (MFCD)

MFCD19792526

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

543.4

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.700

Distribution Coefficient, logD

5.700

Water Solubility, LogSw

-6.17

Polar Surface Area

59.621

Acid Dissociation Constant (pKa)

12.79

Base Dissociation Constant (pKb)

-0.14

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

26.10

V027-7231 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with V027-7231 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V027-7231?
Check Price and Availability of V027-7231, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V027-7231 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V027-7231
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V027-7231
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V027-7231 available by request