V027-8223 Screening compound: 8-benzoyl-3-(butan-2-yl)-1-{[3-(trifluoromethyl)phenyl]methyl}-1,4,8-triazaspiro[4.5]decan-2-one

V027-8223 Screening compound: 8-benzoyl-3-(butan-2-yl)-1-{[3-(trifluoromethyl)phenyl]methyl}-1,4,8-triazaspiro[4.5]decan-2-one
V027-8223 Screening compound: 8-benzoyl-3-(butan-2-yl)-1-{[3-(trifluoromethyl)phenyl]methyl}-1,4,8-triazaspiro[4.5]decan-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound V027-8223
8-benzoyl-3-(butan-2-yl)-1-{[3-(trifluoromethyl)phenyl]methyl}-1,4,8-triazaspiro[4.5]decan-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V027-8223

Molecular Formula

C26H30F3N3O2 (C26 H30 F3 N3 O2)

Compound Name

8-benzoyl-3-(butan-2-yl)-1-{[3-(trifluoromethyl)phenyl]methyl}-1,4,8-triazaspiro[4.5]decan-2-one

IUPAC name

8-benzoyl-3-(butan-2-yl)-1-{[3-(trifluoromethyl)phenyl]methyl}-148-triazaspiro[4.5]decan-2-one

SMILES

CCC(C)C1NC(CC2)(CCN2C(c2ccccc2)=O)N(Cc2cccc(C(F)(F)F)c2)C1=O

InChI

InChI=1S/C26H30F3N3O2/c1-3-18(2)22-24(34)32(17-19-8-7-11-21(16-19)26(27,28)29)25(30-22)12-14-31(15-13-25)23(33)20-9-5-4-6-10-20/h4-11,16,18,22,30H,3,12-15,17H2,1-2H3

InChI Key

YGUDDSAVUICAIK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19817711

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

473.54

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.318

Distribution Coefficient, logD

3.948

Water Solubility, LogSw

-4.26

Polar Surface Area

45.214

Acid Dissociation Constant (pKa)

16.13

Base Dissociation Constant (pKb)

7.53

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

46.20

V027-8223 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with V027-8223 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V027-8223?
Check Price and Availability of V027-8223, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V027-8223 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V027-8223
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V027-8223
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V027-8223 available by request