V027-8525 Screening compound: 2-{5,6-dichloro-2-[(4-fluorophenyl)methyl]-1H-1,3-benzodiazol-1-yl}-N-[2-(pyridin-2-yl)ethyl]acetamide

V027-8525 Screening compound: 2-{5,6-dichloro-2-[(4-fluorophenyl)methyl]-1H-1,3-benzodiazol-1-yl}-N-[2-(pyridin-2-yl)ethyl]acetamide
V027-8525 Screening compound: 2-{5,6-dichloro-2-[(4-fluorophenyl)methyl]-1H-1,3-benzodiazol-1-yl}-N-[2-(pyridin-2-yl)ethyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V027-8525
2-{5,6-dichloro-2-[(4-fluorophenyl)methyl]-1H-1,3-benzodiazol-1-yl}-N-[2-(pyridin-2-yl)ethyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V027-8525

Molecular Formula

C23H19Cl2FN4O (C23 H19 Cl2 FN4 O)

Compound Name

2-{5,6-dichloro-2-[(4-fluorophenyl)methyl]-1H-1,3-benzodiazol-1-yl}-N-[2-(pyridin-2-yl)ethyl]acetamide

IUPAC name

2-{56-dichloro-2-[(4-fluorophenyl)methyl]-1H-13-benzodiazol-1-yl}-N-[2-(pyridin-2-yl)ethyl]acetamide

SMILES

O=C(Cn(c(Cc(cc1)ccc1F)nc1c2)c1cc(Cl)c2Cl)NCCc1ncccc1

InChI

InChI=1S/C23H19Cl2FN4O/c24-18-12-20-21(13-19(18)25)30(22(29-20)11-15-4-6-16(26)7-5-15)14-23(31)28-10-8-17-3-1-2-9-27-17/h1-7,9,12-13H,8,10-11,14H2,(H,28,31)

InChI Key

AXSNOGWMYKTFIC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27632366

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

457.33

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.550

Distribution Coefficient, logD

4.540

Water Solubility, LogSw

-4.55

Polar Surface Area

44.728

Acid Dissociation Constant (pKa)

14.22

Base Dissociation Constant (pKb)

5.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

V027-8525 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with V027-8525 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V027-8525?
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What is the minimum amount of V027-8525 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V027-8525
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V027-8525
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V027-8525 available by request