V027-9417 Screening compound: 1-{4-[6-(3,4-difluorophenoxy)pyrimidin-4-yl]-2-methylpiperazin-1-yl}-2-methylpropan-1-one

V027-9417 Screening compound: 1-{4-[6-(3,4-difluorophenoxy)pyrimidin-4-yl]-2-methylpiperazin-1-yl}-2-methylpropan-1-one
V027-9417 Screening compound: 1-{4-[6-(3,4-difluorophenoxy)pyrimidin-4-yl]-2-methylpiperazin-1-yl}-2-methylpropan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound V027-9417
1-{4-[6-(3,4-difluorophenoxy)pyrimidin-4-yl]-2-methylpiperazin-1-yl}-2-methylpropan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V027-9417

Molecular Formula

C19H22F2N4O2 (C19 H22 F2 N4 O2)

Compound Name

1-{4-[6-(3,4-difluorophenoxy)pyrimidin-4-yl]-2-methylpiperazin-1-yl}-2-methylpropan-1-one

IUPAC name

1-{4-[6-(34-difluorophenoxy)pyrimidin-4-yl]-2-methylpiperazin-1-yl}-2-methylpropan-1-one

SMILES

CC(C)C(N(CC1)C(C)CN1c1cc(Oc(cc2)cc(F)c2F)ncn1)=O

InChI

InChI=1S/C19H22F2N4O2/c1-12(2)19(26)25-7-6-24(10-13(25)3)17-9-18(23-11-22-17)27-14-4-5-15(20)16(21)8-14/h4-5,8-9,11-13H,6-7,10H2,1-3H3/t13-/m0/s1

InChI Key

RISWOTSHWDPPDB-ZDUSSCGKSA-N

MDL Number (MFCD)

MFCD19861034

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

376.41

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.468

Distribution Coefficient, logD

3.468

Water Solubility, LogSw

-3.70

Polar Surface Area

45.559

Acid Dissociation Constant (pKa)

23.36

Base Dissociation Constant (pKb)

1.97

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

42.10

V027-9417 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with V027-9417 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V027-9417?
Check Price and Availability of V027-9417, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V027-9417 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V027-9417
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V027-9417
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V027-9417 available by request