V028-0323 Screening compound: N~4~-[1-benzyl-2-(cyclopropylamino)-2-oxoethyl]-2-[3-(trifluoromethyl)anilino]-1,3-thiazole-4-carboxamide

V028-0323 Screening compound: N~4~-[1-benzyl-2-(cyclopropylamino)-2-oxoethyl]-2-[3-(trifluoromethyl)anilino]-1,3-thiazole-4-carboxamide
V028-0323 Screening compound: N~4~-[1-benzyl-2-(cyclopropylamino)-2-oxoethyl]-2-[3-(trifluoromethyl)anilino]-1,3-thiazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V028-0323
N~4~-[1-benzyl-2-(cyclopropylamino)-2-oxoethyl]-2-[3-(trifluoromethyl)anilino]-1,3-thiazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V028-0323

Molecular Formula

C23H21F3N4O2S (C23 H21 F3 N4 O2 S)

Compound Name

N~4~-[1-benzyl-2-(cyclopropylamino)-2-oxoethyl]-2-[3-(trifluoromethyl)anilino]-1,3-thiazole-4-carboxamide

IUPAC name

N-cyclopropyl-3-phenyl-2-[(2-{[3-(trifluoromethyl)phenyl]amino}-13-thiazol-4-yl)formamido]propanamide

SMILES

O=C(C(Cc1ccccc1)NC(c1csc(Nc2cc(C(F)(F)F)ccc2)n1)=O)NC1CC1

InChI

InChI=1S/C23H21F3N4O2S/c24-23(25,26)15-7-4-8-17(12-15)28-22-30-19(13-33-22)21(32)29-18(20(31)27-16-9-10-16)11-14-5-2-1-3-6-14/h1-8,12-13,16,18H,9-11H2,(H,27,31)(H,28,30)(H,29,32)

InChI Key

PWVVJJGCQIIAEA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19792788

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

474.51

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.401

Distribution Coefficient, logD

5.401

Water Solubility, LogSw

-5.85

Polar Surface Area

67.711

Acid Dissociation Constant (pKa)

12.45

Base Dissociation Constant (pKb)

0.73

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

26.09

V028-0323 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with V028-0323 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V028-0323?
Check Price and Availability of V028-0323, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V028-0323 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V028-0323
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V028-0323
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V028-0323 available by request