V028-1748 Screening compound: 4-[4-(2,4-dimethoxyphenyl)-1-(4-fluorobenzoyl)pyrrolidine-3-carbonyl]morpholine

V028-1748 Screening compound: 4-[4-(2,4-dimethoxyphenyl)-1-(4-fluorobenzoyl)pyrrolidine-3-carbonyl]morpholine
V028-1748 Screening compound: 4-[4-(2,4-dimethoxyphenyl)-1-(4-fluorobenzoyl)pyrrolidine-3-carbonyl]morpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound V028-1748
4-[4-(2,4-dimethoxyphenyl)-1-(4-fluorobenzoyl)pyrrolidine-3-carbonyl]morpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V028-1748

Molecular Formula

C24H27FN2O5 (C24 H27 FN2 O5)

Compound Name

4-[4-(2,4-dimethoxyphenyl)-1-(4-fluorobenzoyl)pyrrolidine-3-carbonyl]morpholine

IUPAC name

4-[4-(24-dimethoxyphenyl)-1-(4-fluorobenzoyl)pyrrolidine-3-carbonyl]morpholine

SMILES

COc1cc(OC)c(C(CN(C2)C(c(cc3)ccc3F)=O)C2C(N2CCOCC2)=O)cc1

InChI

InChI=1S/C24H27FN2O5/c1-30-18-7-8-19(22(13-18)31-2)20-14-27(23(28)16-3-5-17(25)6-4-16)15-21(20)24(29)26-9-11-32-12-10-26/h3-8,13,20-21H,9-12,14-15H2,1-2H3

InChI Key

OGILSLWVJZSOHK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19831543

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

442.49

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.266

Distribution Coefficient, logD

2.266

Water Solubility, LogSw

-2.90

Polar Surface Area

56.579

Acid Dissociation Constant (pKa)

21.09

Base Dissociation Constant (pKb)

-2.15

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

41.70

V028-1748 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Inhibitors of beta-Catenin Signaling (7445 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with V028-1748 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V028-1748?
Check Price and Availability of V028-1748, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V028-1748 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V028-1748
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V028-1748
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V028-1748 available by request