V028-2377 Screening compound: ethyl 4-(2,4-dichlorophenyl)-1-ethyl-6-[(3-methyl-4-{[4-(trifluoromethyl)phenyl]carbamoyl}piperazin-1-yl)methyl]-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

V028-2377 Screening compound: ethyl 4-(2,4-dichlorophenyl)-1-ethyl-6-[(3-methyl-4-{[4-(trifluoromethyl)phenyl]carbamoyl}piperazin-1-yl)methyl]-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
V028-2377 Screening compound: ethyl 4-(2,4-dichlorophenyl)-1-ethyl-6-[(3-methyl-4-{[4-(trifluoromethyl)phenyl]carbamoyl}piperazin-1-yl)methyl]-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound V028-2377
ethyl 4-(2,4-dichlorophenyl)-1-ethyl-6-[(3-methyl-4-{[4-(trifluoromethyl)phenyl]carbamoyl}piperazin-1-yl)methyl]-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V028-2377

Molecular Formula

C29H32Cl2F3N5O4 (C29 H32 Cl2 F3 N5 O4)

Compound Name

ethyl 4-(2,4-dichlorophenyl)-1-ethyl-6-[(3-methyl-4-{[4-(trifluoromethyl)phenyl]carbamoyl}piperazin-1-yl)methyl]-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

IUPAC name

ethyl 4-(24-dichlorophenyl)-1-ethyl-6-[(3-methyl-4-{[4-(trifluoromethyl)phenyl]carbamoyl}piperazin-1-yl)methyl]-2-oxo-1234-tetrahydropyrimidine-5-carboxylate

SMILES

CCN(C(CN(CC1)CC(C)N1C(Nc1ccc(C(F)(F)F)cc1)=O)=C(C(c(ccc(Cl)c1)c1Cl)N1)C(OCC)=O)C1=O

InChI

InChI=1S/C29H32Cl2F3N5O4/c1-4-38-23(24(26(40)43-5-2)25(36-28(38)42)21-11-8-19(30)14-22(21)31)16-37-12-13-39(17(3)15-37)27(41)35-20-9-6-18(7-10-20)29(32,33)34/h6-11,14,17,25H,4-5,12-13,15-16H2,1-3H3,(H,35,41)(H,36,42)

InChI Key

CVFUAMKPHJWZPJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19813368

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

642.51

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

6.003

Distribution Coefficient, logD

4.358

Water Solubility, LogSw

-6.23

Polar Surface Area

76.977

Acid Dissociation Constant (pKa)

9.24

Base Dissociation Constant (pKb)

9.03

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

41.40

V028-2377 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with V028-2377 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V028-2377?
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What is the minimum amount of V028-2377 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V028-2377
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V028-2377
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V028-2377 available by request