V028-4733 Screening compound: ethyl 3-({3-[3-(4-tert-butylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}carbamoyl)propanoate

V028-4733 Screening compound: ethyl 3-({3-[3-(4-tert-butylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}carbamoyl)propanoate
V028-4733 Screening compound: ethyl 3-({3-[3-(4-tert-butylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}carbamoyl)propanoate alternative view

Chemical Structure Depiction of ChemDiv screening compound V028-4733
ethyl 3-({3-[3-(4-tert-butylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}carbamoyl)propanoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V028-4733

Molecular Formula

C25H30N2O4S (C25 H30 N2 O4 S)

Compound Name

ethyl 3-({3-[3-(4-tert-butylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}carbamoyl)propanoate

IUPAC name

ethyl 3-({3-[3-(4-tert-butylphenyl)-4-oxo-13-thiazolidin-2-yl]phenyl}carbamoyl)propanoate

SMILES

CCOC(CCC(Nc1cccc(C(N2c3ccc(C(C)(C)C)cc3)SCC2=O)c1)=O)=O

InChI

InChI=1S/C25H30N2O4S/c1-5-31-23(30)14-13-21(28)26-19-8-6-7-17(15-19)24-27(22(29)16-32-24)20-11-9-18(10-12-20)25(2,3)4/h6-12,15,24H,5,13-14,16H2,1-4H3,(H,26,28)/t24-/m0/s1

InChI Key

IZIVNNQCNSONPA-DEOSSOPVSA-N

MDL Number (MFCD)

MFCD19861514

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

454.59

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.761

Distribution Coefficient, logD

4.761

Water Solubility, LogSw

-4.40

Polar Surface Area

59.441

Acid Dissociation Constant (pKa)

12.10

Base Dissociation Constant (pKb)

3.20

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

40.00

V028-4733 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with V028-4733 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V028-4733?
Check Price and Availability of V028-4733, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V028-4733 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V028-4733
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V028-4733
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V028-4733 available by request