V028-7218 Screening compound: 6,8-dichloro-2-ethyl-N-[2-(pyrrolidin-1-yl)ethyl]quinazolin-4-amine

V028-7218 Screening compound: 6,8-dichloro-2-ethyl-N-[2-(pyrrolidin-1-yl)ethyl]quinazolin-4-amine
V028-7218 Screening compound: 6,8-dichloro-2-ethyl-N-[2-(pyrrolidin-1-yl)ethyl]quinazolin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound V028-7218
6,8-dichloro-2-ethyl-N-[2-(pyrrolidin-1-yl)ethyl]quinazolin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V028-7218

Molecular Formula

C16H20Cl2N4 (C16 H20 Cl2 N4)

Compound Name

6,8-dichloro-2-ethyl-N-[2-(pyrrolidin-1-yl)ethyl]quinazolin-4-amine

IUPAC name

68-dichloro-2-ethyl-N-[2-(pyrrolidin-1-yl)ethyl]quinazolin-4-amine

SMILES

CCc1nc(NCCN2CCCC2)c(cc(cc2Cl)Cl)c2n1

InChI

InChI=1S/C16H20Cl2N4/c1-2-14-20-15-12(9-11(17)10-13(15)18)16(21-14)19-5-8-22-6-3-4-7-22/h9-10H,2-8H2,1H3,(H,19,20,21)

InChI Key

QQMDQRGELQOMFN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD20495812

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

339.27

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.371

Distribution Coefficient, logD

2.130

Water Solubility, LogSw

-4.56

Polar Surface Area

35.350

Acid Dissociation Constant (pKa)

15.07

Base Dissociation Constant (pKb)

9.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

V028-7218 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS BBB Library (22607 compounds)

Cardiovascular Library (22201 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with V028-7218 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V028-7218?
Check Price and Availability of V028-7218, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V028-7218 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V028-7218
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V028-7218
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V028-7218 available by request