V028-8494 Screening compound: 2,4-dichloro-N-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1,3-thiazol-2-yl}benzamide

V028-8494 Screening compound: 2,4-dichloro-N-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1,3-thiazol-2-yl}benzamide
V028-8494 Screening compound: 2,4-dichloro-N-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1,3-thiazol-2-yl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V028-8494
2,4-dichloro-N-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1,3-thiazol-2-yl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V028-8494

Molecular Formula

C20H17Cl2N5O2S (C20 H17 Cl2 N5 O2 S)

Compound Name

2,4-dichloro-N-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1,3-thiazol-2-yl}benzamide

IUPAC name

24-dichloro-N-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]-13-thiazol-2-yl}benzamide

SMILES

O=C(c1csc(NC(c(ccc(Cl)c2)c2Cl)=O)n1)N(CC1)CCN1c1ncccc1

InChI

InChI=1S/C20H17Cl2N5O2S/c21-13-4-5-14(15(22)11-13)18(28)25-20-24-16(12-30-20)19(29)27-9-7-26(8-10-27)17-3-1-2-6-23-17/h1-6,11-12H,7-10H2,(H,24,25,28)

InChI Key

KURGFQANBWZUKP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19976260

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

462.36

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.567

Distribution Coefficient, logD

3.538

Water Solubility, LogSw

-4.78

Polar Surface Area

61.796

Acid Dissociation Constant (pKa)

6.41

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

V028-8494 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

CNS Targets (44014 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • Kinases
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with V028-8494 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V028-8494?
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What is the minimum amount of V028-8494 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V028-8494
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V028-8494
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V028-8494 available by request