V029-2877 Screening compound: 6-(4-fluorobenzoyl)-N-methyl-2-(morpholin-4-yl)-N-(propan-2-yl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-4-amine

V029-2877 Screening compound: 6-(4-fluorobenzoyl)-N-methyl-2-(morpholin-4-yl)-N-(propan-2-yl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-4-amine
V029-2877 Screening compound: 6-(4-fluorobenzoyl)-N-methyl-2-(morpholin-4-yl)-N-(propan-2-yl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound V029-2877
6-(4-fluorobenzoyl)-N-methyl-2-(morpholin-4-yl)-N-(propan-2-yl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V029-2877

Molecular Formula

C22H28FN5O2 (C22 H28 FN5 O2)

Compound Name

6-(4-fluorobenzoyl)-N-methyl-2-(morpholin-4-yl)-N-(propan-2-yl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-4-amine

IUPAC name

6-(4-fluorobenzoyl)-N-methyl-2-(morpholin-4-yl)-N-(propan-2-yl)-5H6H7H8H-pyrido[43-d]pyrimidin-4-amine

SMILES

CC(C)N(C)c1c(CN(CC2)C(c(cc3)ccc3F)=O)c2nc(N2CCOCC2)n1

InChI

InChI=1S/C22H28FN5O2/c1-15(2)26(3)20-18-14-28(21(29)16-4-6-17(23)7-5-16)9-8-19(18)24-22(25-20)27-10-12-30-13-11-27/h4-7,15H,8-14H2,1-3H3

InChI Key

QZTLHCLIXGQXOS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19932895

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

413.5

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.758

Distribution Coefficient, logD

2.757

Water Solubility, LogSw

-2.94

Polar Surface Area

49.618

Acid Dissociation Constant (pKa)

20.03

Base Dissociation Constant (pKb)

4.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

V029-2877 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anticancer Library (62698 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with V029-2877 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V029-2877?
Check Price and Availability of V029-2877, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V029-2877 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V029-2877
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V029-2877
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V029-2877 available by request