V029-7462 Screening compound: 2,4-difluoro-N-(6-{4-[(4-hydroxy-3-methoxyphenyl)methyl]piperazin-1-yl}pyridin-3-yl)benzamide

V029-7462 Screening compound: 2,4-difluoro-N-(6-{4-[(4-hydroxy-3-methoxyphenyl)methyl]piperazin-1-yl}pyridin-3-yl)benzamide
V029-7462 Screening compound: 2,4-difluoro-N-(6-{4-[(4-hydroxy-3-methoxyphenyl)methyl]piperazin-1-yl}pyridin-3-yl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V029-7462
2,4-difluoro-N-(6-{4-[(4-hydroxy-3-methoxyphenyl)methyl]piperazin-1-yl}pyridin-3-yl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V029-7462

Molecular Formula

C24H24F2N4O3 (C24 H24 F2 N4 O3)

Compound Name

2,4-difluoro-N-(6-{4-[(4-hydroxy-3-methoxyphenyl)methyl]piperazin-1-yl}pyridin-3-yl)benzamide

IUPAC name

24-difluoro-N-(6-{4-[(4-hydroxy-3-methoxyphenyl)methyl]piperazin-1-yl}pyridin-3-yl)benzamide

SMILES

COc(cc(CN(CC1)CCN1c(cc1)ncc1NC(c(ccc(F)c1)c1F)=O)cc1)c1O

InChI

InChI=1S/C24H24F2N4O3/c1-33-22-12-16(2-6-21(22)31)15-29-8-10-30(11-9-29)23-7-4-18(14-27-23)28-24(32)19-5-3-17(25)13-20(19)26/h2-7,12-14,31H,8-11,15H2,1H3,(H,28,32)

InChI Key

SNLADRXBXGZDOZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19912020

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

454.48

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.656

Distribution Coefficient, logD

2.933

Water Solubility, LogSw

-3.57

Polar Surface Area

63.102

Acid Dissociation Constant (pKa)

8.74

Base Dissociation Constant (pKb)

8.03

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

V029-7462 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with V029-7462 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V029-7462?
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What is the minimum amount of V029-7462 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V029-7462
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V029-7462
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V029-7462 available by request