V030-5749 Screening compound: 4-[6-(2,4-difluorobenzoyl)-4-(4-methylpiperazin-1-yl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]morpholine

V030-5749 Screening compound: 4-[6-(2,4-difluorobenzoyl)-4-(4-methylpiperazin-1-yl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]morpholine
V030-5749 Screening compound: 4-[6-(2,4-difluorobenzoyl)-4-(4-methylpiperazin-1-yl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]morpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound V030-5749
4-[6-(2,4-difluorobenzoyl)-4-(4-methylpiperazin-1-yl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]morpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V030-5749

Molecular Formula

C23H28F2N6O2 (C23 H28 F2 N6 O2)

Compound Name

4-[6-(2,4-difluorobenzoyl)-4-(4-methylpiperazin-1-yl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]morpholine

IUPAC name

4-[6-(24-difluorobenzoyl)-4-(4-methylpiperazin-1-yl)-5H6H7H8H-pyrido[43-d]pyrimidin-2-yl]morpholine

SMILES

CN(CC1)CCN1c1c(CN(CC2)C(c(ccc(F)c3)c3F)=O)c2nc(N2CCOCC2)n1

InChI

InChI=1S/C23H28F2N6O2/c1-28-6-8-29(9-7-28)21-18-15-31(22(32)17-3-2-16(24)14-19(17)25)5-4-20(18)26-23(27-21)30-10-12-33-13-11-30/h2-3,14H,4-13,15H2,1H3

InChI Key

LMOQARHXVZJPDJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19909079

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

458.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.511

Distribution Coefficient, logD

1.330

Water Solubility, LogSw

-2.86

Polar Surface Area

53.771

Acid Dissociation Constant (pKa)

19.80

Base Dissociation Constant (pKb)

8.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

52.20

V030-5749 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with V030-5749 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V030-5749?
Check Price and Availability of V030-5749, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V030-5749 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V030-5749
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V030-5749
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V030-5749 available by request