Y010-1194 Screening compound: 5-hydroxy-N-[2-(1H-indol-3-yl)ethyl]-[1,2,3]triazolo[1,5-a]quinazoline-3-carboxamide

Y010-1194 Screening compound: 5-hydroxy-N-[2-(1H-indol-3-yl)ethyl]-[1,2,3]triazolo[1,5-a]quinazoline-3-carboxamide
Y010-1194 Screening compound: 5-hydroxy-N-[2-(1H-indol-3-yl)ethyl]-[1,2,3]triazolo[1,5-a]quinazoline-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Y010-1194
5-hydroxy-N-[2-(1H-indol-3-yl)ethyl]-[1,2,3]triazolo[1,5-a]quinazoline-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Y010-1194

Molecular Formula

C20H16N6O2 (C20 H16 N6 O2)

Compound Name

5-hydroxy-N-[2-(1H-indol-3-yl)ethyl]-[1,2,3]triazolo[1,5-a]quinazoline-3-carboxamide

IUPAC name

5-hydroxy-N-[2-(1H-indol-3-yl)ethyl]-[123]triazolo[15-a]quinazoline-3-carboxamide

SMILES

Oc1nc2c(C(NCCc3c[nH]c4c3cccc4)=O)nnn2c2c1cccc2

InChI

InChI=1S/C20H16N6O2/c27-19-14-6-2-4-8-16(14)26-18(23-19)17(24-25-26)20(28)21-10-9-12-11-22-15-7-3-1-5-13(12)15/h1-8,11,22H,9-10H2,(H,21,28)(H,23,27)

InChI Key

QMWIJIGEIDBNBU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09992767

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

372.39

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.028

Distribution Coefficient, logD

0.313

Water Solubility, LogSw

-2.47

Polar Surface Area

83.553

Acid Dissociation Constant (pKa)

5.69

Base Dissociation Constant (pKb)

-0.08

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.00

Y010-1194 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Indole Derivatives (10091 compounds)

SmartTM Library (51161 compounds)

Inhibitors of beta-Catenin Signaling (7445 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with Y010-1194 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Y010-1194?
Check Price and Availability of Y010-1194, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Y010-1194 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Y010-1194
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Y010-1194
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Y010-1194 available by request