Y010-1218 Screening compound: 5-amino-1-[4-(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamido)phenyl]-1H-1,2,3-triazole-4-carboxamide

Y010-1218 Screening compound: 5-amino-1-[4-(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamido)phenyl]-1H-1,2,3-triazole-4-carboxamide
Y010-1218 Screening compound: 5-amino-1-[4-(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamido)phenyl]-1H-1,2,3-triazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Y010-1218
5-amino-1-[4-(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamido)phenyl]-1H-1,2,3-triazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Y010-1218

Molecular Formula

C14H14N8O5S (C14 H14 N8 O5 S)

Compound Name

5-amino-1-[4-(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamido)phenyl]-1H-1,2,3-triazole-4-carboxamide

IUPAC name

5-amino-1-[4-(6-methyl-24-dioxo-1234-tetrahydropyrimidine-5-sulfonamido)phenyl]-1H-123-triazole-4-carboxamide

SMILES

CC(NC(NC1=O)=O)=C1S(Nc(cc1)ccc1-n1nnc(C(N)=O)c1N)(=O)=O

InChI

InChI=1S/C14H14N8O5S/c1-6-10(13(24)18-14(25)17-6)28(26,27)20-7-2-4-8(5-3-7)22-11(15)9(12(16)23)19-21-22/h2-5,20H,15H2,1H3,(H2,16,23)(H2,17,18,24,25)

InChI Key

YVHGSJPEJRQGCH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09992796

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

406.38

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

7.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

13

Partition Coefficient, logP

-1.675

Distribution Coefficient, logD

-4.145

Water Solubility, LogSw

-2.13

Polar Surface Area

169.575

Acid Dissociation Constant (pKa)

4.93

Base Dissociation Constant (pKb)

-2.06

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

7.10

Y010-1218 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

KRAS-Targeted Library (16000 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with Y010-1218 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Y010-1218?
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What is the minimum amount of Y010-1218 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Y010-1218
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Y010-1218
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Y010-1218 available by request