Y020-1008 Screening compound: 2-[(6-ethoxy-4-methylquinazolin-2-yl)amino]-6-methyl-5-[(naphthalen-1-yl)methyl]-3,4-dihydropyrimidin-4-one

Y020-1008 Screening compound: 2-[(6-ethoxy-4-methylquinazolin-2-yl)amino]-6-methyl-5-[(naphthalen-1-yl)methyl]-3,4-dihydropyrimidin-4-one
Y020-1008 Screening compound: 2-[(6-ethoxy-4-methylquinazolin-2-yl)amino]-6-methyl-5-[(naphthalen-1-yl)methyl]-3,4-dihydropyrimidin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound Y020-1008
2-[(6-ethoxy-4-methylquinazolin-2-yl)amino]-6-methyl-5-[(naphthalen-1-yl)methyl]-3,4-dihydropyrimidin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Y020-1008

Molecular Formula

C27H25N5O2 (C27 H25 N5 O2)

Compound Name

2-[(6-ethoxy-4-methylquinazolin-2-yl)amino]-6-methyl-5-[(naphthalen-1-yl)methyl]-3,4-dihydropyrimidin-4-one

IUPAC name

2-[(6-ethoxy-4-methylquinazolin-2-yl)amino]-6-methyl-5-[(naphthalen-1-yl)methyl]-34-dihydropyrimidin-4-one

SMILES

CCOc1ccc2nc(NC(N3)=NC(C)=C(Cc4cccc5ccccc45)C3=O)nc(C)c2c1

InChI

InChI=1S/C27H25N5O2/c1-4-34-20-12-13-24-22(15-20)16(2)28-26(30-24)32-27-29-17(3)23(25(33)31-27)14-19-10-7-9-18-8-5-6-11-21(18)19/h5-13,15H,4,14H2,1-3H3,(H2,28,29,30,31,32,33)

InChI Key

ITSHZHXMWMMGQS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04164910

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

451.53

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.508

Distribution Coefficient, logD

5.478

Water Solubility, LogSw

-6.48

Polar Surface Area

70.787

Acid Dissociation Constant (pKa)

8.56

Base Dissociation Constant (pKb)

4.79

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.50

Y020-1008 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with Y020-1008 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Y020-1008?
Check Price and Availability of Y020-1008, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Y020-1008 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Y020-1008
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Y020-1008
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Y020-1008 available by request