Y020-2977 Screening compound: N-(4-fluorophenyl)-2-(morpholin-4-yl)-4,7-dioxo-3H,4H,5H,6H,7H,8H-pyrido[2,3-d]pyrimidine-5-carboxamide

Y020-2977 Screening compound: N-(4-fluorophenyl)-2-(morpholin-4-yl)-4,7-dioxo-3H,4H,5H,6H,7H,8H-pyrido[2,3-d]pyrimidine-5-carboxamide
Y020-2977 Screening compound: N-(4-fluorophenyl)-2-(morpholin-4-yl)-4,7-dioxo-3H,4H,5H,6H,7H,8H-pyrido[2,3-d]pyrimidine-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Y020-2977
N-(4-fluorophenyl)-2-(morpholin-4-yl)-4,7-dioxo-3H,4H,5H,6H,7H,8H-pyrido[2,3-d]pyrimidine-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Y020-2977

Molecular Formula

C18H18FN5O4 (C18 H18 FN5 O4)

Compound Name

N-(4-fluorophenyl)-2-(morpholin-4-yl)-4,7-dioxo-3H,4H,5H,6H,7H,8H-pyrido[2,3-d]pyrimidine-5-carboxamide

IUPAC name

N-(4-fluorophenyl)-2-(morpholin-4-yl)-47-dioxo-3H4H5H6H7H8H-pyrido[23-d]pyrimidine-5-carboxamide

SMILES

O=C(C(CC(N1)=O)C(C(N2)=O)=C1N=C2N1CCOCC1)Nc(cc1)ccc1F

InChI

InChI=1S/C18H18FN5O4/c19-10-1-3-11(4-2-10)20-16(26)12-9-13(25)21-15-14(12)17(27)23-18(22-15)24-5-7-28-8-6-24/h1-4,12H,5-9H2,(H,20,26)(H2,21,22,23,25,27)/t12-/m1/s1

InChI Key

VWNMWZVTAUNPAJ-GFCCVEGCSA-N

MDL Number (MFCD)

MFCD11082141

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

387.37

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

-0.284

Distribution Coefficient, logD

-0.311

Water Solubility, LogSw

-1.80

Polar Surface Area

92.596

Acid Dissociation Constant (pKa)

8.59

Base Dissociation Constant (pKb)

-4.65

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

33.30

Y020-2977 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with Y020-2977 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Y020-2977?
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What is the minimum amount of Y020-2977 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Y020-2977
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Y020-2977
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Y020-2977 available by request