Y020-2978 Screening compound: N-(3,5-dichlorophenyl)-2-(morpholin-4-yl)-4,7-dioxo-3H,4H,5H,6H,7H,8H-pyrido[2,3-d]pyrimidine-5-carboxamide

Y020-2978 Screening compound: N-(3,5-dichlorophenyl)-2-(morpholin-4-yl)-4,7-dioxo-3H,4H,5H,6H,7H,8H-pyrido[2,3-d]pyrimidine-5-carboxamide
Y020-2978 Screening compound: N-(3,5-dichlorophenyl)-2-(morpholin-4-yl)-4,7-dioxo-3H,4H,5H,6H,7H,8H-pyrido[2,3-d]pyrimidine-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Y020-2978
N-(3,5-dichlorophenyl)-2-(morpholin-4-yl)-4,7-dioxo-3H,4H,5H,6H,7H,8H-pyrido[2,3-d]pyrimidine-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Y020-2978

Molecular Formula

C18H17Cl2N5O4 (C18 H17 Cl2 N5 O4)

Compound Name

N-(3,5-dichlorophenyl)-2-(morpholin-4-yl)-4,7-dioxo-3H,4H,5H,6H,7H,8H-pyrido[2,3-d]pyrimidine-5-carboxamide

IUPAC name

N-(35-dichlorophenyl)-2-(morpholin-4-yl)-47-dioxo-3H4H5H6H7H8H-pyrido[23-d]pyrimidine-5-carboxamide

SMILES

O=C(C(CC(N1)=O)C(C(N2)=O)=C1N=C2N1CCOCC1)Nc1cc(Cl)cc(Cl)c1

InChI

InChI=1S/C18H17Cl2N5O4/c19-9-5-10(20)7-11(6-9)21-16(27)12-8-13(26)22-15-14(12)17(28)24-18(23-15)25-1-3-29-4-2-25/h5-7,12H,1-4,8H2,(H,21,27)(H2,22,23,24,26,28)/t12-/m1/s1

InChI Key

WEGLFFPWERSCCK-GFCCVEGCSA-N

MDL Number (MFCD)

MFCD11082149

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

438.27

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.218

Distribution Coefficient, logD

1.191

Water Solubility, LogSw

-2.75

Polar Surface Area

92.596

Acid Dissociation Constant (pKa)

8.59

Base Dissociation Constant (pKb)

-4.65

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

33.30

Y020-2978 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

KRAS-Targeted Library (16000 compounds)

PI3K-Targeted Library (17255 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with Y020-2978 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Y020-2978?
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What is the minimum amount of Y020-2978 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Y020-2978
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Y020-2978
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Y020-2978 available by request