Y020-4355 Screening compound: 5-(4-chlorophenyl)-2-(4-methylpiperazin-1-yl)-3H,4H-pyrido[2,3-d]pyrimidin-4-one

Y020-4355 Screening compound: 5-(4-chlorophenyl)-2-(4-methylpiperazin-1-yl)-3H,4H-pyrido[2,3-d]pyrimidin-4-one
Y020-4355 Screening compound: 5-(4-chlorophenyl)-2-(4-methylpiperazin-1-yl)-3H,4H-pyrido[2,3-d]pyrimidin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound Y020-4355
5-(4-chlorophenyl)-2-(4-methylpiperazin-1-yl)-3H,4H-pyrido[2,3-d]pyrimidin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Y020-4355

Molecular Formula

C18H18ClN5O (C18 H18 ClN5 O)

Compound Name

5-(4-chlorophenyl)-2-(4-methylpiperazin-1-yl)-3H,4H-pyrido[2,3-d]pyrimidin-4-one

IUPAC name

5-(4-chlorophenyl)-2-(4-methylpiperazin-1-yl)-3H4H-pyrido[23-d]pyrimidin-4-one

SMILES

CN(CC1)CCN1C(N1)=Nc2nccc(-c(cc3)ccc3Cl)c2C1=O

InChI

InChI=1S/C18H18ClN5O/c1-23-8-10-24(11-9-23)18-21-16-15(17(25)22-18)14(6-7-20-16)12-2-4-13(19)5-3-12/h2-7H,8-11H2,1H3,(H,20,21,22,25)

InChI Key

CYAONLMCAHPFOH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD18488627

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

355.83

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.758

Distribution Coefficient, logD

1.387

Water Solubility, LogSw

-3.89

Polar Surface Area

50.786

Acid Dissociation Constant (pKa)

9.43

Base Dissociation Constant (pKb)

8.75

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

Y020-4355 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with Y020-4355 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Y020-4355?
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What is the minimum amount of Y020-4355 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Y020-4355
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Y020-4355
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Y020-4355 available by request