Y020-6140 Screening compound: 4,7-dioxo-2-(piperidin-1-yl)-5-(pyridin-3-yl)-3H,4H,5H,6H,7H,8H-pyrido[2,3-d]pyrimidine-6-carbonitrile

Y020-6140 Screening compound: 4,7-dioxo-2-(piperidin-1-yl)-5-(pyridin-3-yl)-3H,4H,5H,6H,7H,8H-pyrido[2,3-d]pyrimidine-6-carbonitrile
Y020-6140 Screening compound: 4,7-dioxo-2-(piperidin-1-yl)-5-(pyridin-3-yl)-3H,4H,5H,6H,7H,8H-pyrido[2,3-d]pyrimidine-6-carbonitrile alternative view

Chemical Structure Depiction of ChemDiv screening compound Y020-6140
4,7-dioxo-2-(piperidin-1-yl)-5-(pyridin-3-yl)-3H,4H,5H,6H,7H,8H-pyrido[2,3-d]pyrimidine-6-carbonitrile

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Y020-6140

Molecular Formula

C18H18N6O2 (C18 H18 N6 O2)

Compound Name

4,7-dioxo-2-(piperidin-1-yl)-5-(pyridin-3-yl)-3H,4H,5H,6H,7H,8H-pyrido[2,3-d]pyrimidine-6-carbonitrile

IUPAC name

47-dioxo-2-(piperidin-1-yl)-5-(pyridin-3-yl)-3H4H5H6H7H8H-pyrido[23-d]pyrimidine-6-carbonitrile

SMILES

N#CC(C(c1cnccc1)C(C(N1)=O)=C(N2)N=C1N1CCCCC1)C2=O

InChI

InChI=1S/C18H18N6O2/c19-9-12-13(11-5-4-6-20-10-11)14-15(21-16(12)25)22-18(23-17(14)26)24-7-2-1-3-8-24/h4-6,10,12-13H,1-3,7-8H2,(H2,21,22,23,25,26)

InChI Key

KITLSNSDVATFGU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD18204563

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

350.38

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

0.087

Distribution Coefficient, logD

0.067

Water Solubility, LogSw

-1.12

Polar Surface Area

87.955

Acid Dissociation Constant (pKa)

8.73

Base Dissociation Constant (pKb)

2.73

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

38.90

Y020-6140 in Drug Discovery

Included in Screening Libraries

BRD4 Targeted Library (4534 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cardiovascular
  • Metabolic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Others
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with Y020-6140 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Y020-6140?
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What is the minimum amount of Y020-6140 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Y020-6140
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Y020-6140
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Y020-6140 available by request