Y020-8493 Screening compound: 4-amino-N-(4-chlorophenyl)-2-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidine-5-carbothioamide

Y020-8493 Screening compound: 4-amino-N-(4-chlorophenyl)-2-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidine-5-carbothioamide
Y020-8493 Screening compound: 4-amino-N-(4-chlorophenyl)-2-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidine-5-carbothioamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Y020-8493
4-amino-N-(4-chlorophenyl)-2-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidine-5-carbothioamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Y020-8493

Molecular Formula

C15H16ClN5O2S (C15 H16 ClN5 O2 S)

Compound Name

4-amino-N-(4-chlorophenyl)-2-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidine-5-carbothioamide

IUPAC name

4-amino-N-(4-chlorophenyl)-2-(morpholin-4-yl)-6-oxo-16-dihydropyrimidine-5-carbothioamide

SMILES

NC(N=C(N1)N2CCOCC2)=C(C(Nc(cc2)ccc2Cl)=S)C1=O

InChI

InChI=1S/C15H16ClN5O2S/c16-9-1-3-10(4-2-9)18-14(24)11-12(17)19-15(20-13(11)22)21-5-7-23-8-6-21/h1-4H,5-8H2,(H,18,24)(H3,17,19,20,22)

InChI Key

NXUMPRNRFAMLLP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15195192

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

365.84

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

4.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.471

Distribution Coefficient, logD

0.646

Water Solubility, LogSw

-2.69

Polar Surface Area

76.671

Acid Dissociation Constant (pKa)

6.65

Base Dissociation Constant (pKb)

2.40

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.70

Y020-8493 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

PI3K-Targeted Library (17255 compounds)

Akt-Targeted Library (14764 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Proteases
  • Kinases
  • Kinases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with Y020-8493 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Y020-8493?
Check Price and Availability of Y020-8493, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Y020-8493 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Y020-8493
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Y020-8493
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Y020-8493 available by request