Y043-2665 Screening compound: 2-{[6,7-dimethoxy-3,4-dihydro-2(1H)-isoquinolinyl]methyl}-6-(2-fluorophenyl)-3(2H)-pyridazinone

Y043-2665 Screening compound: 2-{[6,7-dimethoxy-3,4-dihydro-2(1H)-isoquinolinyl]methyl}-6-(2-fluorophenyl)-3(2H)-pyridazinone
Y043-2665 Screening compound: 2-{[6,7-dimethoxy-3,4-dihydro-2(1H)-isoquinolinyl]methyl}-6-(2-fluorophenyl)-3(2H)-pyridazinone alternative view

Chemical Structure Depiction of ChemDiv screening compound Y043-2665
2-{[6,7-dimethoxy-3,4-dihydro-2(1H)-isoquinolinyl]methyl}-6-(2-fluorophenyl)-3(2H)-pyridazinone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Y043-2665

Molecular Formula

C22H22FN3O3 (C22 H22 FN3 O3)

Compound Name

2-{[6,7-dimethoxy-3,4-dihydro-2(1H)-isoquinolinyl]methyl}-6-(2-fluorophenyl)-3(2H)-pyridazinone

IUPAC name

2-[(67-dimethoxy-1234-tetrahydroisoquinolin-2-yl)methyl]-6-(2-fluorophenyl)-23-dihydropyridazin-3-one

SMILES

COc1cc(CCN(CN(C(C=C2)=O)N=C2c(cccc2)c2F)C2)c2cc1OC

InChI

InChI=1S/C22H22FN3O3/c1-28-20-11-15-9-10-25(13-16(15)12-21(20)29-2)14-26-22(27)8-7-19(24-26)17-5-3-4-6-18(17)23/h3-8,11-12H,9-10,13-14H2,1-2H3

InChI Key

PKUMGOOABDVMLF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD22203011

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

395.43

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.228

Distribution Coefficient, logD

3.143

Water Solubility, LogSw

-3.53

Polar Surface Area

48.896

Acid Dissociation Constant (pKa)

25.43

Base Dissociation Constant (pKb)

6.74

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.27

Y043-2665 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with Y043-2665 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Y043-2665?
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What is the minimum amount of Y043-2665 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Y043-2665
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Y043-2665
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Y043-2665 available by request