Y043-5078 Screening compound: 5-methoxy-N-[2-(4-phenyl-1,3-thiazol-2-yl)ethyl]-1H-indole-2-carboxamide

Y043-5078 Screening compound: 5-methoxy-N-[2-(4-phenyl-1,3-thiazol-2-yl)ethyl]-1H-indole-2-carboxamide
Y043-5078 Screening compound: 5-methoxy-N-[2-(4-phenyl-1,3-thiazol-2-yl)ethyl]-1H-indole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Y043-5078
5-methoxy-N-[2-(4-phenyl-1,3-thiazol-2-yl)ethyl]-1H-indole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Y043-5078

Molecular Formula

C21H19N3O2S (C21 H19 N3 O2 S)

Compound Name

5-methoxy-N-[2-(4-phenyl-1,3-thiazol-2-yl)ethyl]-1H-indole-2-carboxamide

IUPAC name

5-methoxy-N-[2-(4-phenyl-13-thiazol-2-yl)ethyl]-1H-indole-2-carboxamide

SMILES

COc(cc1)cc2c1[nH]c(C(NCCc1nc(-c3ccccc3)cs1)=O)c2

InChI

InChI=1S/C21H19N3O2S/c1-26-16-7-8-17-15(11-16)12-18(23-17)21(25)22-10-9-20-24-19(13-27-20)14-5-3-2-4-6-14/h2-8,11-13,23H,9-10H2,1H3,(H,22,25)

InChI Key

RXKUGLMBSPSIQW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28059293

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

377.47

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.637

Distribution Coefficient, logD

4.637

Water Solubility, LogSw

-4.59

Polar Surface Area

51.615

Acid Dissociation Constant (pKa)

14.28

Base Dissociation Constant (pKb)

0.01

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.29

Y043-5078 in Drug Discovery

Included in Screening Libraries

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with Y043-5078 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Y043-5078?
Check Price and Availability of Y043-5078, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Y043-5078 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Y043-5078
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Y043-5078
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Y043-5078 available by request