Y043-8815 Screening compound: 5-amino-4-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-1-[(1-methyl-1H-imidazol-2-yl)(phenyl)methyl]-1,2-dihydro-3H-pyrrol-3-one

Y043-8815 Screening compound: 5-amino-4-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-1-[(1-methyl-1H-imidazol-2-yl)(phenyl)methyl]-1,2-dihydro-3H-pyrrol-3-one
Y043-8815 Screening compound: 5-amino-4-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-1-[(1-methyl-1H-imidazol-2-yl)(phenyl)methyl]-1,2-dihydro-3H-pyrrol-3-one alternative view

Chemical Structure Depiction of ChemDiv screening compound Y043-8815
5-amino-4-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-1-[(1-methyl-1H-imidazol-2-yl)(phenyl)methyl]-1,2-dihydro-3H-pyrrol-3-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Y043-8815

Molecular Formula

C24H20ClN5OS (C24 H20 ClN5 OS)

Compound Name

5-amino-4-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-1-[(1-methyl-1H-imidazol-2-yl)(phenyl)methyl]-1,2-dihydro-3H-pyrrol-3-one

IUPAC name

5-amino-4-[4-(4-chlorophenyl)-13-thiazol-2-yl]-1-[(1-methyl-1H-imidazol-2-yl)(phenyl)methyl]-23-dihydro-1H-pyrrol-3-one

SMILES

Cn1c(C(c2ccccc2)N(CC2=O)C(N)=C2c2nc(-c(cc3)ccc3Cl)cs2)ncc1

InChI

InChI=1S/C24H20ClN5OS/c1-29-12-11-27-23(29)21(16-5-3-2-4-6-16)30-13-19(31)20(22(30)26)24-28-18(14-32-24)15-7-9-17(25)10-8-15/h2-12,14,21H,13,26H2,1H3/t21-/m1/s1

InChI Key

ZZZIFTFDIKSPJL-OAQYLSRUSA-N

MDL Number (MFCD)

MFCD28986318

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

461.97

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.723

Distribution Coefficient, logD

4.723

Water Solubility, LogSw

-5.02

Polar Surface Area

58.071

Acid Dissociation Constant (pKa)

16.05

Base Dissociation Constant (pKb)

2.60

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

12.50

Y043-8815 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with Y043-8815 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Y043-8815?
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What is the minimum amount of Y043-8815 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Y043-8815
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Y043-8815
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Y043-8815 available by request