Y200-0063 Screening compound: methyl 4-(2,4-dimethoxyphenyl)-2-(pyridine-4-amido)thiophene-3-carboxylate

Y200-0063 Screening compound: methyl 4-(2,4-dimethoxyphenyl)-2-(pyridine-4-amido)thiophene-3-carboxylate
Y200-0063 Screening compound: methyl 4-(2,4-dimethoxyphenyl)-2-(pyridine-4-amido)thiophene-3-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound Y200-0063
methyl 4-(2,4-dimethoxyphenyl)-2-(pyridine-4-amido)thiophene-3-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Y200-0063

Molecular Formula

C20H18N2O5S (C20 H18 N2 O5 S)

Compound Name

methyl 4-(2,4-dimethoxyphenyl)-2-(pyridine-4-amido)thiophene-3-carboxylate

IUPAC name

methyl 4-(24-dimethoxyphenyl)-2-(pyridine-4-amido)thiophene-3-carboxylate

SMILES

COC(c1c(NC(c2ccncc2)=O)scc1-c(ccc(OC)c1)c1OC)=O

InChI

InChI=1S/C20H18N2O5S/c1-25-13-4-5-14(16(10-13)26-2)15-11-28-19(17(15)20(24)27-3)22-18(23)12-6-8-21-9-7-12/h4-11H,1-3H3,(H,22,23)

InChI Key

NPLJJAFSEBAYKD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08724536

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

398.44

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.853

Distribution Coefficient, logD

2.279

Water Solubility, LogSw

-3.43

Polar Surface Area

68.629

Acid Dissociation Constant (pKa)

6.96

Base Dissociation Constant (pKb)

2.35

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.00

Y200-0063 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Anticancer Library (62698 compounds)

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with Y200-0063 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Y200-0063?
Check Price and Availability of Y200-0063, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Y200-0063 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Y200-0063
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Y200-0063
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Y200-0063 available by request