Y200-0180 Screening compound: [6-methyl-2-(2-pyridyl)-4-quinolyl][4-(2-thienylmethyl)piperazino]methanone

Y200-0180 Screening compound: [6-methyl-2-(2-pyridyl)-4-quinolyl][4-(2-thienylmethyl)piperazino]methanone
Y200-0180 Screening compound: [6-methyl-2-(2-pyridyl)-4-quinolyl][4-(2-thienylmethyl)piperazino]methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound Y200-0180
[6-methyl-2-(2-pyridyl)-4-quinolyl][4-(2-thienylmethyl)piperazino]methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Y200-0180

Molecular Formula

C25H24N4OS (C25 H24 N4 OS)

Compound Name

[6-methyl-2-(2-pyridyl)-4-quinolyl][4-(2-thienylmethyl)piperazino]methanone

IUPAC name

6-methyl-2-(pyridin-2-yl)-4-{4-[(thiophen-2-yl)methyl]piperazine-1-carbonyl}quinoline

SMILES

Cc(cc1c(C(N2CCN(Cc3cccs3)CC2)=O)c2)ccc1nc2-c1ncccc1

InChI

InChI=1S/C25H24N4OS/c1-18-7-8-22-20(15-18)21(16-24(27-22)23-6-2-3-9-26-23)25(30)29-12-10-28(11-13-29)17-19-5-4-14-31-19/h2-9,14-16H,10-13,17H2,1H3

InChI Key

ZETBCZATLLGBFE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08569582

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

428.56

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.269

Distribution Coefficient, logD

4.259

Water Solubility, LogSw

-4.17

Polar Surface Area

38.553

Acid Dissociation Constant (pKa)

26.71

Base Dissociation Constant (pKb)

5.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

Y200-0180 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with Y200-0180 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Y200-0180?
Check Price and Availability of Y200-0180, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Y200-0180 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Y200-0180
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Y200-0180
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Y200-0180 available by request