Y200-1006 Screening compound: N~4~-(1,5-dimethyl-1H-pyrazol-3-yl)-6-methyl-2-(4-pyridyl)-4-quinolinecarboxamide

Y200-1006 Screening compound: N~4~-(1,5-dimethyl-1H-pyrazol-3-yl)-6-methyl-2-(4-pyridyl)-4-quinolinecarboxamide
Y200-1006 Screening compound: N~4~-(1,5-dimethyl-1H-pyrazol-3-yl)-6-methyl-2-(4-pyridyl)-4-quinolinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Y200-1006
N~4~-(1,5-dimethyl-1H-pyrazol-3-yl)-6-methyl-2-(4-pyridyl)-4-quinolinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Y200-1006

Molecular Formula

C21H19N5O (C21 H19 N5 O)

Compound Name

N~4~-(1,5-dimethyl-1H-pyrazol-3-yl)-6-methyl-2-(4-pyridyl)-4-quinolinecarboxamide

IUPAC name

N-(15-dimethyl-1H-pyrazol-3-yl)-6-methyl-2-(pyridin-4-yl)quinoline-4-carboxamide

SMILES

Cc1cc(NC(c2cc(-c3ccncc3)nc3ccc(C)cc23)=O)nn1C

InChI

InChI=1S/C21H19N5O/c1-13-4-5-18-16(10-13)17(12-19(23-18)15-6-8-22-9-7-15)21(27)24-20-11-14(2)26(3)25-20/h4-12H,1-3H3,(H,24,25,27)

InChI Key

SEYCRXRURWGVDZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04138101

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

357.41

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.616

Distribution Coefficient, logD

3.609

Water Solubility, LogSw

-3.75

Polar Surface Area

55.871

Acid Dissociation Constant (pKa)

9.24

Base Dissociation Constant (pKb)

4.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.29

Y200-1006 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with Y200-1006 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Y200-1006?
Check Price and Availability of Y200-1006, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Y200-1006 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Y200-1006
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Y200-1006
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Y200-1006 available by request