Z066-0383 Screening compound: N-{3-[4-(2,4-dimethylphenyl)piperazin-1-yl]propyl}-3-(pyrimidin-5-yl)-1,2,4-oxadiazole-5-carboxamide

Z066-0383 Screening compound: N-{3-[4-(2,4-dimethylphenyl)piperazin-1-yl]propyl}-3-(pyrimidin-5-yl)-1,2,4-oxadiazole-5-carboxamide
Z066-0383 Screening compound: N-{3-[4-(2,4-dimethylphenyl)piperazin-1-yl]propyl}-3-(pyrimidin-5-yl)-1,2,4-oxadiazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z066-0383
N-{3-[4-(2,4-dimethylphenyl)piperazin-1-yl]propyl}-3-(pyrimidin-5-yl)-1,2,4-oxadiazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z066-0383

Molecular Formula

C22H27N7O2 (C22 H27 N7 O2)

Compound Name

N-{3-[4-(2,4-dimethylphenyl)piperazin-1-yl]propyl}-3-(pyrimidin-5-yl)-1,2,4-oxadiazole-5-carboxamide

IUPAC name

N-{3-[4-(24-dimethylphenyl)piperazin-1-yl]propyl}-3-(pyrimidin-5-yl)-124-oxadiazole-5-carboxamide

SMILES

Cc(cc1)cc(C)c1N1CCN(CCCNC(c2nc(-c3cncnc3)no2)=O)CC1

InChI

InChI=1S/C22H27N7O2/c1-16-4-5-19(17(2)12-16)29-10-8-28(9-11-29)7-3-6-25-21(30)22-26-20(27-31-22)18-13-23-15-24-14-18/h4-5,12-15H,3,6-11H2,1-2H3,(H,25,30)

InChI Key

VRKUEEDEORVPLW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27634467

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.5

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.133

Distribution Coefficient, logD

0.987

Water Solubility, LogSw

-2.43

Polar Surface Area

83.862

Acid Dissociation Constant (pKa)

14.34

Base Dissociation Constant (pKb)

8.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.90

Z066-0383 in Drug Discovery

Included in Screening Libraries

Human Kinases Annotated Library (2415 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with Z066-0383 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z066-0383?
Check Price and Availability of Z066-0383, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z066-0383 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z066-0383
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z066-0383
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z066-0383 available by request