Z066-0385 Screening compound: N-{3-[4-(2,5-dimethylphenyl)piperazin-1-yl]propyl}-3-(pyrimidin-4-yl)-1,2,4-oxadiazole-5-carboxamide

Z066-0385 Screening compound: N-{3-[4-(2,5-dimethylphenyl)piperazin-1-yl]propyl}-3-(pyrimidin-4-yl)-1,2,4-oxadiazole-5-carboxamide
Z066-0385 Screening compound: N-{3-[4-(2,5-dimethylphenyl)piperazin-1-yl]propyl}-3-(pyrimidin-4-yl)-1,2,4-oxadiazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z066-0385
N-{3-[4-(2,5-dimethylphenyl)piperazin-1-yl]propyl}-3-(pyrimidin-4-yl)-1,2,4-oxadiazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z066-0385

Molecular Formula

C22H27N7O2 (C22 H27 N7 O2)

Compound Name

N-{3-[4-(2,5-dimethylphenyl)piperazin-1-yl]propyl}-3-(pyrimidin-4-yl)-1,2,4-oxadiazole-5-carboxamide

IUPAC name

N-{3-[4-(25-dimethylphenyl)piperazin-1-yl]propyl}-3-(pyrimidin-4-yl)-124-oxadiazole-5-carboxamide

SMILES

Cc1cc(N2CCN(CCCNC(c3nc(-c4ncncc4)no3)=O)CC2)c(C)cc1

InChI

InChI=1S/C22H27N7O2/c1-16-4-5-17(2)19(14-16)29-12-10-28(11-13-29)9-3-7-24-21(30)22-26-20(27-31-22)18-6-8-23-15-25-18/h4-6,8,14-15H,3,7,9-13H2,1-2H3,(H,24,30)

InChI Key

ZMJUIRJLUOQHOS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27634468

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.5

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.224

Distribution Coefficient, logD

1.077

Water Solubility, LogSw

-2.52

Polar Surface Area

83.303

Acid Dissociation Constant (pKa)

14.26

Base Dissociation Constant (pKb)

8.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.90

Z066-0385 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with Z066-0385 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z066-0385?
Check Price and Availability of Z066-0385, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z066-0385 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z066-0385
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z066-0385
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z066-0385 available by request