Z128-0004 Screening compound: N~6~-[6-(aminosulfonyl)-3-pyridyl]-3-isobutyl-4-oxo-3,4-dihydro-6-quinazolinecarboxamide

Z128-0004 Screening compound: N~6~-[6-(aminosulfonyl)-3-pyridyl]-3-isobutyl-4-oxo-3,4-dihydro-6-quinazolinecarboxamide
Z128-0004 Screening compound: N~6~-[6-(aminosulfonyl)-3-pyridyl]-3-isobutyl-4-oxo-3,4-dihydro-6-quinazolinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z128-0004
N~6~-[6-(aminosulfonyl)-3-pyridyl]-3-isobutyl-4-oxo-3,4-dihydro-6-quinazolinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z128-0004

Molecular Formula

C18H19N5O4S (C18 H19 N5 O4 S)

Compound Name

N~6~-[6-(aminosulfonyl)-3-pyridyl]-3-isobutyl-4-oxo-3,4-dihydro-6-quinazolinecarboxamide

IUPAC name

n/a

SMILES

CC(C)CN(C=Nc(cc1)c2cc1C(Nc(cc1)cnc1S(N)(=O)=O)=O)C2=O

InChI

InChI=1S/C18H19N5O4S/c1-11(2)9-23-10-21-15-5-3-12(7-14(15)18(23)25)17(24)22-13-4-6-16(20-8-13)28(19,26)27/h3-8,10-11H,9H2,1-2H3,(H,22,24)(H2,19,26,27)

InChI Key

PCQIPHNZDGBTIQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27634537

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

401.45

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.337

Distribution Coefficient, logD

0.896

Water Solubility, LogSw

-2.55

Polar Surface Area

109.217

Acid Dissociation Constant (pKa)

7.15

Base Dissociation Constant (pKb)

0.97

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

Z128-0004 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with Z128-0004 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z128-0004?
Check Price and Availability of Z128-0004, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z128-0004 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z128-0004
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z128-0004
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z128-0004 available by request