Z128-0008 Screening compound: 3-(2-methoxyethyl)-4-oxo-N-(6-sulfamoylpyridin-3-yl)-3,4-dihydroquinazoline-6-carboxamide

Z128-0008 Screening compound: 3-(2-methoxyethyl)-4-oxo-N-(6-sulfamoylpyridin-3-yl)-3,4-dihydroquinazoline-6-carboxamide
Z128-0008 Screening compound: 3-(2-methoxyethyl)-4-oxo-N-(6-sulfamoylpyridin-3-yl)-3,4-dihydroquinazoline-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z128-0008
3-(2-methoxyethyl)-4-oxo-N-(6-sulfamoylpyridin-3-yl)-3,4-dihydroquinazoline-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z128-0008

Molecular Formula

C17H17N5O5S (C17 H17 N5 O5 S)

Compound Name

3-(2-methoxyethyl)-4-oxo-N-(6-sulfamoylpyridin-3-yl)-3,4-dihydroquinazoline-6-carboxamide

IUPAC name

3-(2-methoxyethyl)-4-oxo-N-(6-sulfamoylpyridin-3-yl)-34-dihydroquinazoline-6-carboxamide

SMILES

COCCN(C=Nc(cc1)c2cc1C(Nc(cc1)cnc1S(N)(=O)=O)=O)C2=O

InChI

InChI=1S/C17H17N5O5S/c1-27-7-6-22-10-20-14-4-2-11(8-13(14)17(22)24)16(23)21-12-3-5-15(19-9-12)28(18,25)26/h2-5,8-10H,6-7H2,1H3,(H,21,23)(H2,18,25,26)

InChI Key

YDNVUIJLGBLMLA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27634539

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

403.42

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

0.017

Distribution Coefficient, logD

-0.424

Water Solubility, LogSw

-2.50

Polar Surface Area

117.538

Acid Dissociation Constant (pKa)

7.15

Base Dissociation Constant (pKb)

1.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.60

Z128-0008 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with Z128-0008 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z128-0008?
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What is the minimum amount of Z128-0008 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z128-0008
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z128-0008
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z128-0008 available by request