Z128-0013 Screening compound: 4-oxo-3-[(pyridin-4-yl)methyl]-N-(6-sulfamoylpyridin-3-yl)-3,4-dihydroquinazoline-6-carboxamide

Z128-0013 Screening compound: 4-oxo-3-[(pyridin-4-yl)methyl]-N-(6-sulfamoylpyridin-3-yl)-3,4-dihydroquinazoline-6-carboxamide
Z128-0013 Screening compound: 4-oxo-3-[(pyridin-4-yl)methyl]-N-(6-sulfamoylpyridin-3-yl)-3,4-dihydroquinazoline-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z128-0013
4-oxo-3-[(pyridin-4-yl)methyl]-N-(6-sulfamoylpyridin-3-yl)-3,4-dihydroquinazoline-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z128-0013

Molecular Formula

C20H16N6O4S (C20 H16 N6 O4 S)

Compound Name

4-oxo-3-[(pyridin-4-yl)methyl]-N-(6-sulfamoylpyridin-3-yl)-3,4-dihydroquinazoline-6-carboxamide

IUPAC name

4-oxo-3-[(pyridin-4-yl)methyl]-N-(6-sulfamoylpyridin-3-yl)-34-dihydroquinazoline-6-carboxamide

SMILES

NS(c(cc1)ncc1NC(c(cc1)cc2c1N=CN(Cc1ccncc1)C2=O)=O)(=O)=O

InChI

InChI=1S/C20H16N6O4S/c21-31(29,30)18-4-2-15(10-23-18)25-19(27)14-1-3-17-16(9-14)20(28)26(12-24-17)11-13-5-7-22-8-6-13/h1-10,12H,11H2,(H,25,27)(H2,21,29,30)

InChI Key

HOHAWLUVRLHSIL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27634542

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

436.45

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

0.086

Distribution Coefficient, logD

-0.355

Water Solubility, LogSw

-2.27

Polar Surface Area

118.374

Acid Dissociation Constant (pKa)

7.15

Base Dissociation Constant (pKb)

4.85

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.00

Z128-0013 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with Z128-0013 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z128-0013?
Check Price and Availability of Z128-0013, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z128-0013 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z128-0013
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z128-0013
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z128-0013 available by request