Z128-0017 Screening compound: N-(5-methyl-1,2-oxazol-3-yl)-4-oxo-3-[(pyridin-4-yl)methyl]-3,4-dihydroquinazoline-6-carboxamide

Z128-0017 Screening compound: N-(5-methyl-1,2-oxazol-3-yl)-4-oxo-3-[(pyridin-4-yl)methyl]-3,4-dihydroquinazoline-6-carboxamide
Z128-0017 Screening compound: N-(5-methyl-1,2-oxazol-3-yl)-4-oxo-3-[(pyridin-4-yl)methyl]-3,4-dihydroquinazoline-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z128-0017
N-(5-methyl-1,2-oxazol-3-yl)-4-oxo-3-[(pyridin-4-yl)methyl]-3,4-dihydroquinazoline-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z128-0017

Molecular Formula

C19H15N5O3 (C19 H15 N5 O3)

Compound Name

N-(5-methyl-1,2-oxazol-3-yl)-4-oxo-3-[(pyridin-4-yl)methyl]-3,4-dihydroquinazoline-6-carboxamide

IUPAC name

N-(5-methyl-12-oxazol-3-yl)-4-oxo-3-[(pyridin-4-yl)methyl]-34-dihydroquinazoline-6-carboxamide

SMILES

Cc1cc(NC(c(cc2)cc3c2N=CN(Cc2ccncc2)C3=O)=O)no1

InChI

InChI=1S/C19H15N5O3/c1-12-8-17(23-27-12)22-18(25)14-2-3-16-15(9-14)19(26)24(11-21-16)10-13-4-6-20-7-5-13/h2-9,11H,10H2,1H3,(H,22,23,25)

InChI Key

WEHYFKMRFRGAAH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27634544

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

361.36

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.429

Distribution Coefficient, logD

-0.020

Water Solubility, LogSw

-2.24

Polar Surface Area

80.654

Acid Dissociation Constant (pKa)

5.97

Base Dissociation Constant (pKb)

4.85

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.50

Z128-0017 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with Z128-0017 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z128-0017?
Check Price and Availability of Z128-0017, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z128-0017 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z128-0017
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z128-0017
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z128-0017 available by request