Z217-0012 Screening compound: 2-{[1-(4-methoxyphenyl)-3-methyl-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl](methyl)amino}-N-[(pyridin-2-yl)methyl]acetamide

Z217-0012 Screening compound: 2-{[1-(4-methoxyphenyl)-3-methyl-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl](methyl)amino}-N-[(pyridin-2-yl)methyl]acetamide
Z217-0012 Screening compound: 2-{[1-(4-methoxyphenyl)-3-methyl-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl](methyl)amino}-N-[(pyridin-2-yl)methyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z217-0012
2-{[1-(4-methoxyphenyl)-3-methyl-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl](methyl)amino}-N-[(pyridin-2-yl)methyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z217-0012

Molecular Formula

C21H22N6O2S (C21 H22 N6 O2 S)

Compound Name

2-{[1-(4-methoxyphenyl)-3-methyl-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl](methyl)amino}-N-[(pyridin-2-yl)methyl]acetamide

IUPAC name

2-{[1-(4-methoxyphenyl)-3-methyl-1H-pyrazolo[34-d][13]thiazol-5-yl](methyl)amino}-N-[(pyridin-2-yl)methyl]acetamide

SMILES

Cc(c1c2nc(N(C)CC(NCc3ncccc3)=O)s1)nn2-c(cc1)ccc1OC

InChI

InChI=1S/C21H22N6O2S/c1-14-19-20(27(25-14)16-7-9-17(29-3)10-8-16)24-21(30-19)26(2)13-18(28)23-12-15-6-4-5-11-22-15/h4-11H,12-13H2,1-3H3,(H,23,28)

InChI Key

QDUYSBIUXXERHO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27634548

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

422.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.816

Distribution Coefficient, logD

2.815

Water Solubility, LogSw

-3.36

Polar Surface Area

69.352

Acid Dissociation Constant (pKa)

12.91

Base Dissociation Constant (pKb)

4.74

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

Z217-0012 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with Z217-0012 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z217-0012?
Check Price and Availability of Z217-0012, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z217-0012 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z217-0012
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z217-0012
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z217-0012 available by request